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Antigen
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F-box and leucine-rich repeat protein 8 (FBXL8)
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Gene ID
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55336
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Immunogen
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FBXL8 (AAH14414, 1 a.a. ~ 375 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) MAEPGEGLPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDTKISCECE LEGMLPPYLSACLDHIHNLRLEFEPSRKPSRRAAIELLMVLAGRAPGLRGLRLEC RGEKPLFDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELH SLFLDNSTLVGSVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFA LLALRCACPEDARASPLPNEAWVALRRRHPGLAVELELEPALPAESVTRVLQPAV PVAALRLNLSGDTVGPVRFAAHHYAATLCALEVRAAASAELNAALEELAARCAAL REVHCFCVVSHSVLDAFRAHCPRLRTYTLKLTREPHPWRPTLVA*
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Reactivity
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Human
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Antibody Type
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Monoclonal
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Isotype
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IgG1 Kappa »Matching secondary antibodies
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Description
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F-box and leucine-rich repeat protein 8 This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. Mouse monoclonal antibody raised against a full length recombinant FBXL8. Synonyms: FBL8, FLJ11278, MGC19959
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Clone
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20
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Host
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Mouse
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