FBG3 (F Box 3) antibody

Overview

Antigen	FBG3 (F Box 3)
Antibody Type	Polyclonal
Format	Liquid
Isotype	IgG »Matching secondary antibodies
Description	F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
Host	Rabbit
Specificity	Reacts with residues 103-119 (EWKVEDLSRDQRKEFPN) of the human FBG3 protein. High cross reactivity: 94% identical to mouse and rat FBG3.

Application	ELISA, Western Blotting (WB)
Application Notes	Western blot-Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Concentration	1 mg/ml
Purity	Affinity purified IgG
Buffer	PBS containing 0.02% sodium azide.
Storage	Maintain at +2-8 C for 3 months or at -20 C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
Restrictions	For research use only

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