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Product details for FOXO4 (phospho S193) (Human) antibody
FOXO4 (phospho S193) (Human) antibody
Overview
| Antigen: | FOXO4 (phospho S193) |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human, Hamster |
| Host: | Rabbit |
| Quantity: | |
| Price: | 368,42 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN150570 |
| Availability: | 7 to 10 days until shipment |
Additional Information: FOXO4 (phospho S193) (Human) antibody
| Antigen | FOXO4 (phospho S193) |
| Immunogen | Available on request. |
| Reactivity | Human, Hamster |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | The forkhead family of transcription factors is involved in tumorigenesis in rhabdomyosarcoma and acute leukemias. Within the family, three members (FKHR, AFX, AND FKHRL1) have sequence similarity to the nematode homolog Daf 16, recently shown to mediate signaling via a pathway involving IGFR1, P13-K and Akt. There are three potential Akt phosphorylation sites on the FKHR proteins. One site, FKHR Ser256 is found in the Forkhead domain and the other two are outside this domain. Recent studies show that phosphorylation of FKHR family members by Akt promotes cell survival. Phosphorylation regulates FKHR nuclear translocation and target gene transcription. Insulin also stimulates FKHR phosphorylation at Ser253. |
| Host | Rabbit |
| Specificity | This antibody recognizes the phosphorylated Ser193 of AFX. It does not react with non-phosphorylated AFX. |
Application Details: FOXO4 (phospho S193) (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | WB: Use at a concentration of 1-2 ug/ml. In Western blot, this antibody detects a band of approximately 62 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.5 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide |
| Storage | Store at -20 C. For long term storage, aliquot and refreeze at -70 C. Avoid repeated freeze/defrost cycles |
| Restrictions | For research use only |
External Information: FOXO4 (phospho S193) (Human) antibody
| Google Scholar | Find more references for antigen FOXO4 (phospho S193) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen FOXO4 (phospho S193) (Bioinformatic Harvester (EMBL)) |
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