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Product details for Galectin-3 (38B2) (Human) antibody
Galectin-3 (38B2) (Human) antibody
Overview
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| Antigen: | Galectin-3 (38B2) |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry (IHC), Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 315,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN180085 |
| Availability: | 10 days until shipment |
Additional Information: Galectin-3 (38B2) (Human) antibody
| Antigen | Galectin-3 (38B2) |
| Immunogen | Recombinant Galectin-3 protein |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Galectin is widely distributed in nematodes, insects, and porifers, as well as vertebrates, and it has also been found to be present in true fungi. Galectin does not just occur in the cytoplasm, it is also present in the nucleus, on the cell surface, in the extracellular matrix, etc., and it is thought to be involved in many biological phenomena, including development, differentiation, morphogenesis, tumor metastasis, cell death, and RNA splicing. Galectin-3 is a -galactoside-binding protein that has been named IgE-binding protein, CBP35, CBP30, Mac-2, L-29, L-31, L34, etc., and structurally it is a chimera-type lectin composed of a sugar-chain-binding domain (galectin domain) and a non-lectin domain. Its biological function is still uncertain, but many studies that should elucidate its function have been performed, and as a result participation of galectin-3 has been demonstrated in the biological phenomena of cell growth, adhesion, metastasis, and apoptosis. For example, a positive correlation has been shown between galectin-3 expression and the degree of malignant transformation in certain types of cell lines. A positive correlation has also recently been shown between galectin-3 expression and degree of malignancy in certain types of malignant tumors, and measurement of galectin-3 is expected to possibly serve as an index of degree of tumor malignancy. |
| Clone | 38B2 |
| Host | Mouse |
Application Details: Galectin-3 (38B2) (Human) antibody
| Application | Immunohistochemistry (IHC), Western Blotting (WB) |
| Application Notes | This antibody can be used for Immunohistochemistry in concentration of about 2-5 ug/mL by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) method, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of about 2-5 ug/mlL. Reference:1. Ochieng J, Platt D, Tait L, Hogan V, Raz T, Carmi P, Raz A. Structure-function relationship of a recombinant human galactoside-binding protein. Biochemistry. 1-993 Apr 2-7,32(16):4455-60. 2-002 Sep 1-9,1572(2-3):263-73. |
| Purification | Protein A |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 mL distilled water will be added to the product, then its concentration comes to 100 ug/mL |
| Storage | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| Research Area | Cancer |
| Restrictions | For Research Use only |
External Information: Galectin-3 (38B2) (Human) antibody
| Google Scholar | Find more references for clone 38B2 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Galectin-3 (38B2) (Bioinformatic Harvester (EMBL)) |
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