Product details for  ICAD (N-term) (Mouse (Murine)) antibody
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ICAD (N-term) (Mouse (Murine)) antibody

Overview

Antigen: ICAD/DFF45 (N-term)
Antibody Type: Polyclonal
Application: Western Blotting (WB)
Reactivity: Mouse (Murine)
Host: Rabbit
Quantity: 0.1 mg (0.5 mg/ml)
Price: 320,00 €   (Plus shipping costs and VAT)
Order number: ABIN121557
Availability: Ships in 3 to 10 days
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Additional Information:  ICAD (N-term) (Mouse (Murine)) antibody

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Antigen ICAD/DFF45 (N-term)
Immunogen Synthetic peptide corresponding to amino acids 312-331 of mouse ICAD.
Reactivity Mouse (Murine)
Antibody Type Polyclonal
Format Purified
Host Rabbit
Specificity ICAD (Inhibitor of Caspase-Activated DNase) is the murine homologue of human DFF-45. ICAD is cleaved by Caspase-3, releasing CAD which eventually causes degradation of DNA in the nucleus. This antibody recognises a 45kD band in Western blots.

Application Details:  ICAD (N-term) (Mouse (Murine)) antibody

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Application Western Blotting (WB)
Application Notes Western blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Format Purified
Concentration 0.5 mg/ml
Buffer This antibody is supplied as liquid, affinity purified immunoglobulin fraction in PBS with 0.02% sodium azide as preservative.
Storage Store the antibody at 4-8°C for one month or at –20°C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Apoptosis/Necrosis
Restrictions Research only

Publications:  ICAD (N-term) (Mouse (Murine)) antibody

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Publications Enari, Sakahira, Yokoyama et al.:
"A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD."
In: Nature , Vol. 391, Issue 6662, pp. 43-50, 1998/01 (PubMed)

Wyllie:
"Apoptosis. An endonuclease at last."
In: Nature , Vol. 391, Issue 6662, pp. 20-1, 1998/01 (PubMed)

External Information:  ICAD (N-term) (Mouse (Murine)) antibody

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Google Scholar Find more references for antigen ICAD/DFF45 (N-term) on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen ICAD/DFF45 (N-term) (Bioinformatic Harvester (EMBL))