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Product details for IL1RAcP (Human) antibody
IL1RAcP (Human) antibody
Overview
| Antigen: | Interleukin-1 RAcP (IL-1RAcP) |
| Antibody Type: | Polyclonal |
| Application: | Enzyme Immunoassay (EIA), Western Blotting (WB), Immunoprecipitation (IP) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 360,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN151624 |
| Availability: | Ships in 7 to 10 days |
Additional Information: IL1RAcP (Human) antibody
| Antigen | Interleukin-1 RAcP (IL-1RAcP) |
| Immunogen | Peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identicalto those of mouseand rat origins (1). |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Format | Aff - Purified |
| Description | The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits ofits receptor, IL-1receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP).IL-1RAcP forms a complex with IL-1RI inresponse to IL-1 treatment. The IL-1receptor-associatedkinase (IRAK), which mediates activation of NF-kBinducing kinae(NIK) and of NF-kB, recruits to the IL-1Rcomplex through IL-1RAcP. IL-1 activation ofstress activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP.Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcPis expressed in many tissues. |
| Host | Rabbit |
| Specificity | Detects a band at approximately 66kDa. It has no cross activity to other members in theIL-1 receptor family. Cross-reacts with Human, Rat and Mouse. Not yet tested in other species. |
Application Details: IL1RAcP (Human) antibody
| Application | Enzyme Immunoassay (EIA), Western Blotting (WB), Immunoprecipitation (IP) |
| Application Notes | Suggested working dilutions *ELISA, Western Blot, immunoprecipitation * Investigator should determine optimal working dilutions. ELISA: 0.1 - 1.0 ug/ml. WB: 1/1000 - 1/2000 dilution. IP: 3.0 - 5.0 ug/ml extract from10e7 cells. * Other applications have not been tested. Positive Control:HeLa whole cell lysate |
| Buffer | PBS with 0.02% sodium azide 0.05 mg Immunogen affinity purified Rabbit antisera. |
| Storage | Store at 4 degrees C for up to one year. |
| Restrictions | For Research Use only |
External Information: IL1RAcP (Human) antibody
| Google Scholar | Find more references for antigen Interleukin-1 RAcP (IL-1RAcP) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Interleukin-1 RAcP (IL-1RAcP) (Bioinformatic Harvester (EMBL)) |
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