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Product details for L-Selectin antibody
L-Selectin antibody
Overview
| Antigen: | L-Selectin |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 266,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN131169 |
| Availability: | 7 to 10 days until shipment |
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Additional Information: L-Selectin antibody
| Antigen | L-Selectin |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils. L-Selectin (also called LECAM-1) is required for the binding of lymphocytes to the high endothelial venules of peripheral lymph nodes (and therefore serves as a lymphocyte homing receptor) and for the invasion of neutrophils into sites of inflammation. Whereas E-selectin and P-selectin are expressed by endothelial cells, L-selectin is found only on leukocytes. Soluble L-selectin is shed by activated neutrophils and acts to inhibit leukocyte attachment to endothelium. |
| Host | Rabbit |
| Specificity | L-selectin is heavily glycosylated. It has a calculated M.W. of 37 kDa, however, the protein runs at 75-110 kDa by SDS-PAGE. The antibody recognizes L-selectin in human, mouse, and rat cell lysates. |
Application Details: L-Selectin antibody
| Application | Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
| Application Notes | The antibody can be used for Western blot analysis (1-4 µg/ml), immunoprecipitation (10-20 µg/ml), and immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. |
| Buffer | Supplied as 100 µg (0.5 mg/ml) rabbit anti-L-selectin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 0.02% sodium azide. |
| Research Area | Inflammation, CD Antigens |
| Restrictions | For Research Use Only |
External Information: L-Selectin antibody
| Google Scholar | Find more references for antigen L-Selectin on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen L-Selectin (Bioinformatic Harvester (EMBL)) |
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