Product details for  NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody
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NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody

Overview

Image for NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody
Antigen: NAD(P)H dehydrogenase, quinone 1 (NQO1)
Antibody Type: Monoclonal
Application: Western Blotting (WB), ELISA
Reactivity: Human
Host: Mouse
Quantity: 100 µg
Price: 396,00 €   (Plus shipping costs , €10 dry ice fee and VAT)
Order number: ABIN166045
Availability: Delivery in 7 to 10 days

Additional Information:  NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody

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Antigen NAD(P)H dehydrogenase, quinone 1 (NQO1)
Gene ID 1728
Immunogen NQO1 (AAH07659, 1 a.a. ~ 275 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKD ITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVP AILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDM NVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETP LYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK*
Reactivity Human
Antibody Type Monoclonal
Isotype IgG1 kappa »Matching secondary antibodies
Description NAD(P)H dehydrogenase, quinone 1 This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Mouse monoclonal antibody raised against a full length recombinant NQO1. Synonyms: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Clone 1E3-A6
Host Mouse

Application Details:  NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody

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Application Western Blotting (WB), ELISA
Application Notes Quality Control: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Buffer In 1x PBS, pH 7.2 Western Blot detection against Immunogen (55.88 KDa) .
Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Restrictions For Research Use only

Images:  NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody

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Western Blot detection against Immunogen (55.88 KDa) .

Image for NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody (1)

The detection limit for recombinant GST tagged NQO1 is approximately 0.3ng/ml as a capture antibody.

Image for NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody (2)

External Information:  NAD(P)H dehydrogenase, quinone 1 (NQO1) (Human) antibody

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EMBL Harvester Search human, mouse or rat genome for antigen NQO1 (Bioinformatic Harvester (EMBL))