NF-kappaB (p65) (Human) antibody

Overview

Antigen	NF-kappaB (p65)
Immunogen	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of human RELA
Reactivity	Human
Antibody Type	Polyclonal
Format	Liquid
Isotype	IgG »Matching secondary antibodies
Description	P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.
Host	Rabbit

Application	Western Blotting (WB)
Application Notes	WB: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer. Optimal dilutions should be determined by end-user.
Concentration	1 mg/ml
Purity	Rabbit Ig G is purified by Protein G/A affinity chromatography method.
Buffer	PBS with 2% sucrose
Storage	Store at -20 C or below. Avoid repeat freeze-thaw cycles.
Restrictions	For research use only

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