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Product details for NKIRAS1 (Human) antibody
NKIRAS1 (Human) antibody
Overview
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| Antigen: | NKIRAS1 |
| Antibody Type: | Monoclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Mouse |
| Quantity: | |
| Price: | 349,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN144147 |
| Availability: | 7 to 10 days until shipment |
Additional Information: NKIRAS1 (Human) antibody
| Antigen | NKIRAS1 |
| Immunogen | Synthetic peptide: RVELLKKEIDKFKDKKEV, corresponding to amino acids 96-113 of Human NKIRAS1. |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first genes induced following NF-kB activation is IkBa. Recently, two proteins, kB-Ras1 and kB-Ras2 have been identified. These two proteins interact with PEST domains of IkBa and IkBb and decrease their rate of degradation. |
| Clone | 184C278 |
| Host | Mouse |
Application Details: NKIRAS1 (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | WB: Use at a concentration of 0.5-1 ug/ml. Predicted molecular weight: 23 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.5 mg/ml |
| Purity | Protein G purified |
| Buffer | Preservative: 0.02% Sodium AzideConstituents: PBS |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Restrictions | For research use only |
External Information: NKIRAS1 (Human) antibody
| Google Scholar | Find more references for clone 184C278 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen NKIRAS1 (Bioinformatic Harvester (EMBL)) |
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