NMDA Receptor 2C (Human) antibody

Overview

Antigen	NMDA Receptor 2C
Immunogen	This product was raised against a 17 kDa N-terminal fusion protein representing amino acids 25-130 of rat NMDAR2C.
Reactivity	Human, Rat
Antibody Type	Polyclonal
Format	Liquid
Description	The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid AMPA) are known as kainate/AMPA receptors (K/AMPAR).
Host	Rabbit
Specificity	Labels the 140 kDa band representing NR2C in Western blots of cerebellum. It also labels the 180 kDa NR2A and NR2B bands. Immunolabeling is blocked by preadsorption of the antibody with the c-terminal fusion protein used to generate the antibody.

Application Notes	For WB: Use at a dilution of 1:1,000. A ~48 kDa band can be seen in a Western blot analysis, using rat brain hippocampal homogenate. Not testetd in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Concentration	0.2 mg/ml
Purity	Affinity purified
Buffer	N/A
Storage	After reconstitution store at -20 C. Avoid repeated freeze-thaw cycles.
Restrictions	For research use only

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