Nab2 (Human) antibody

Overview

Antigen	Nab2
Immunogen	Full length protein (Human Nab2)
Reactivity	Human, Mouse (Murine)
Antibody Type	Monoclonal
Format	Liquid
Isotype	IgG1 »Matching secondary antibodies
Description	NGFIA-binding protein 1 (NAB1) has been shown to repress EGR1 and EGR2 transcriptional activity and to interact with a 34-amino acid inhibitory region, named the R1 domain, contained in EGR1. Nab2 can repress the transcriptional activity of both EGR1 and EGR2 in vitro. Northern blotting of RNA isolated from various adult mouse tissues showed that Nab2 is most highly expressed in the brain and thymus, with significant expression also in the spleen, kidney, heart, and testes, there is little expression in the liver. Northern and Western blotting indicated that Nab2 expression is regulated by some of the same stimuli that induce EGR1 expression.
Clone	Cl-1C4
Host	Mouse

Application	Western Blotting (WB)
Application Notes	For WB: Use at a dilution of 1:1000. Detects a band of approximately 56-65 kDa. The molecular weight may vary according to the phosphorylation. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Format	Liquid
Concentration	Not determined
Purity	Tissue culture supernatant
Buffer	Phosphate-buffered saline containing 0.2% gelatin, 0.01% thimerosal and 0.1% sodium azide
Storage	Keep as concentrated solution. Store at 4?C short term. For extended storage aliquot and store at -20?C or below. Avoid freeze-thaw cycles.
Restrictions	For research use only

Google Scholar	Find more references for clone cl-1C4 on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen Nab2 (Bioinformatic Harvester (EMBL))