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Product details for OGG1 (8-oxoguanine DNA glycosylase 1) (Human) antibody
OGG1 (8-oxoguanine DNA glycosylase 1) (Human) antibody
Overview
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| Antigen: | OGG1 (8-oxoguanine DNA glycosylase 1) |
| Antibody Type: | Monoclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 315,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN180046 |
| Availability: | 10 days until shipment |
Additional Information: OGG1 (8-oxoguanine DNA glycosylase 1) (Human) antibody
| Antigen | OGG1 (8-oxoguanine DNA glycosylase 1) |
| Immunogen | Recombinant Human OGG1 |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Oxidative damage to DNA has been proposed to have a role in cancer and ageing. Oxygen-free radicals formed during normal aerobic cellular metabolism attack bases in DNA, and 7, 8-dihydro-8-oxoguanine (8-oxoG) is one of the adducts formed. Eukaryotic replicative DNA polymerases replicate DNA containing 8-oxoG by inserting an adenine opposite the lesion, consequently, 8-oxoG is highly mutagenic and causes G:C to T:A transversions. Genetic studies in yeast have indicated a role for mismatch repair in minimizing the incidence of these mutations. In Saccharomyces cerevisiae, deletion of OGG1, encoding a DNA glycosylase that functions in the removal of 8-oxoG when |
| Clone | 7-00E-02 |
| Host | Mouse |
Application Details: OGG1 (8-oxoguanine DNA glycosylase 1) (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | This antibody can be used for western blotting in concentration of 1 ug/ml. Reactivity: confirmed in human OGG1 transfectant Reference:Shinmura K., et al. Expression of the OGG1-type 1a(nuclear form) protein in cancerous and non-cancerous human cells. International Journal of Oncology 2-000 1-6: 7-01-707 |
| Purification | Protein A |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product |
| Storage | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| Restrictions | For Research Use only |
External Information: OGG1 (8-oxoguanine DNA glycosylase 1) (Human) antibody
| Google Scholar | Find more references for clone 7-00E-02 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen OGG1 (8-oxoguanine DNA glycosylase 1) (Bioinformatic Harvester (EMBL)) |
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