P-Glyoprotein antibody

Overview

Antigen	P-Glyoprotein
Immunogen	Multi drug resistant chinese hamster ovary cell line, CHrC5
Antibody Type	Monoclonal
Format	Liquid
Isotype	IgG1 (Mouse) »Matching secondary antibodies
Description	Recognises the 170-180kD P-glycoprotein, a plasma membrane associated molecule which is important in mediating resistance to cytotoxic drugs. In normal tissues P-glycoprotein is expressed in liver, kidney, colon, adrenal gland and lung. In malignant conditions increased expression of P-glycoprotein may be associated with multi-drug resistance, and the detection of this can have important consequences for treatment.
Clone	JSB-1
Host	Mouse
Specificity	Human P-glycoprotein

Application	Immunohistochemistry (IHC)
Application Notes	Immunohistology, Immunohistology:*This product requires protein digestion pre-treatment of paraffin sections e.g. 0.1% pronase, 10 mins.
Concentration	0.25 mg/ml
Buffer	Phosphate buffered saline pH 7.3, containing 0.09% sodium azide and 0.5% bovine serum albumin
Storage	Store at +4 C. DO NOT FREEZE. Should this product contain a precipitate we recommend microcentrifugation before use. This product contains sodium azide : a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Restrictions	For research use only

Google Scholar	Find more references for clone JSB-1 on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen P-Glyoprotein (Bioinformatic Harvester (EMBL))