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Product details for Ube1L (Human) antibody
Ube1L (Human) antibody
Overview
| Antigen: | Ube1L |
| Antibody Type: | Polyclonal |
| Application: | Immunofluorescence (IF), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Rabbit |
| Quantity: | |
| Price: | 388,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN149201 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Ube1L (Human) antibody
| Antigen | Ube1L |
| Immunogen | Synthetic peptide: DCDPRSIHVREDGSLEIGD, corresponding to amino acids 222-240 of Human Ube1L. |
| Reactivity | Human |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | Ube1L is a member of the E1 ubiquitin-activating enzyme family. It is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia. It has been reported that Ube1L acts as the activating enzyme in the ISG15 conjugation pathway. ISG15 is a ubiquitin-like protein and its transcription is induced by interferon treatment. |
| Host | Rabbit |
| Specificity | The specificity of this antibody has been confirmed by immunoblot analyses of Ube1L-transfected CHO cells. CHO cells that did not basally express Ube1L mRNA were transfected with a full-length Ube1L cDNA or an insertless vector. CHO cells transfected with |
Application Details: Ube1L (Human) antibody
| Application | Immunofluorescence (IF), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB) |
| Application Notes | IHC-P: Use at a dilution of 1/1000. IHC-Fr: Use at a dilution of 1/1000. WB: Use at a dilution of 1/500. Detects a band of approximately 112 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Purity | Whole antiserum |
| Buffer | Preservative: 0.05% Sodium AzideConstituents: 30% Glycerol, 0.15M Sodium Chloride, 0.1M Tris-glycine. pH 7.4 |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Restrictions | For research use only |
External Information: Ube1L (Human) antibody
| Google Scholar | Find more references for antigen Ube1L on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Ube1L (Bioinformatic Harvester (EMBL)) |
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