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Product details for X-ray repair complementing defective repair in Chinese ha...
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) (Human) antibody
Overview
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| Antigen: | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) |
| Antibody Type: | Monoclonal |
| Application: | Western Blotting (WB), ELISA |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 396,00 € (Plus shipping costs , €10.00 dry ice fee and VAT) |
| Order number: | ABIN167714 |
| Availability: | Delivery in 7 to 10 days |
Additional Information: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) (Human) antibody
| Antigen | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) |
| Gene ID | 7520 |
| Immunogen | XRCC5 (AAH19027, 1 a.a. ~ 733 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIA LVLFGTDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDA LIVSMDVIQHETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFL PFSLGKEDGSGDRGDGPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDG LDEIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKT WTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQ MKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLIHALD DLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLVYVQLPFMEDLRQYMFSSLKN SKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTTKIPNPRFQRLFQCLL HRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLIEAKKKDQVTA QEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRVLVKQK KASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDT AAVFEEGGDVDDLLDMI* |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Isotype | IgG1 Kappa »Matching secondary antibodies |
| Description | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Mouse monoclonal antibody raised against a full length recombinant XRCC5. Synonyms: KARP-1, KARP1, KU80, KUB2, Ku86, NFIV |
| Clone | 3D8 |
| Host | Mouse |
Application Details: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) (Human) antibody
| Application | Western Blotting (WB), ELISA |
| Application Notes | Quality Control: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Buffer | In 1x PBS, pH 7.2 Western Blot detection against Immunogen (106.26 KDa) . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Restrictions | For Research Use only |
Images: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) (Human) antibody
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Western Blot detection against Immunogen (106.26 KDa) . |
External Information: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa) (XRCC5) (Human) antibody
| Google Scholar | Find more references for clone 3D8 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen XRCC5 (Bioinformatic Harvester (EMBL)) |
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