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Product details for a disintegrin and metalloproteinase domain 17 (tumor necr...
a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
Overview
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| Antigen: | A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry (IHC), ELISA, Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 396,00 € (Plus shipping costs , €10 dry ice fee and VAT) |
| Order number: | ABIN167544 |
| Availability: | Delivery in 7 to 10 days |
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Additional Information: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
| Antigen | A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) |
| Gene ID | 6868 |
| Immunogen | ADAM17 (NP_003174, 215 a.a. ~ 315 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDN AGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDV* |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Isotype | IgG2b Kappa »Matching secondary antibodies |
| Description | ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway. Mouse monoclonal antibody raised against a partial recombinant ADAM17. Synonyms: CD156b, MGC71942, TACE, cSVP |
| Clone | 1F6 |
| Host | Mouse |
Application Details: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
| Application | Immunohistochemistry (IHC), ELISA, Western Blotting (WB) |
| Application Notes | Quality Control: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Buffer | In 1x PBS, pH 7.2 Western Blot detection against Immunogen (37.11 KDa) . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Restrictions | For Research Use only |
Images: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
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Western Blot detection against Immunogen (37.11 KDa) .
Immunoperoxidase of monoclonal antibody to ADAM17 (H00006868-M01) on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
The detection limit for recombinant GST tagged ADAM17 is approximately 3ng/ml as a capture antibody. |
External Information: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
| Google Scholar | Find more references for clone 1F6 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen ADAM17 (Bioinformatic Harvester (EMBL)) |
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