BASKET
HELP
Product details for alpha A Crystallin (Rat) antibody
alpha A Crystallin (Rat) antibody
Overview
| Antigen: | Alpha A Crystallin |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB) |
| Reactivity: | Rat, Bovine |
| Host: | Rabbit |
| Quantity: | |
| Price: | 388,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN148653 |
| Availability: | 7 to 10 days until shipment |
Additional Information: alpha A Crystallin (Rat) antibody
| Antigen | Alpha A Crystallin |
| Immunogen | Purified alpha-A crystallin from bovine lens. |
| Reactivity | Rat, Bovine |
| Antibody Type | Polyclonal |
| Format | Lyophilized |
| Isotype | IgG »Matching secondary antibodies |
| Description | Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index of the lens. The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma. Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products--alpha-A and alpha-B. There are at least 5 different proteins comprising the beta-crystallins. The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens. Alpha-Crystallin comprises 40% of total lens protein composition. In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation. It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a str |
| Host | Rabbit |
| Specificity | This antibody does not detect the unphosphorylated form of the protein. |
Application Details: alpha A Crystallin (Rat) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB) |
| Application Notes | IHC-P: Use at a concentration of 10 ug/ml. WB: Use at a concentration of 0.1 ug/ml. Detects a band of approximately 20 kDa representing alpha-A crystallin from bovine lens samples. Immunohistochemical staining of alpha-A crystallin in rat thymus samples results in staining of epithelial reticular cells. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 0.05% Sodium AzideConstituents: PBS, 30mg/ml BSA |
| Restrictions | For research use only |
External Information: alpha A Crystallin (Rat) antibody
| Google Scholar | Find more references for antigen alpha A Crystallin on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen alpha A Crystallin (Bioinformatic Harvester (EMBL)) |
browse antibodies by
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
