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Product details for alpha SNAP (Human) antibody
alpha SNAP (Human) antibody
Overview
| Antigen: | Alpha SNAP |
| Antibody Type: | Monoclonal |
| Application: | ELISA, Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Rat |
| Host: | Mouse |
| Quantity: | |
| Price: | 388,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN144144 |
| Availability: | 7 to 10 days until shipment |
Additional Information: alpha SNAP (Human) antibody
| Antigen | Alpha SNAP |
| Immunogen | Recombinant full length Human alpha SNAP. |
| Reactivity | Human, Rat |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF), are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNAP. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process. alpha SNAP is expressed in all mammalian tissues. |
| Clone | 4-00E-004 |
| Host | Mouse |
| Specificity | Does not cross react with beta-SNAP. |
Application Details: alpha SNAP (Human) antibody
| Application | ELISA, Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | ELISA: Use at an assay dependent dilution. IP: Use at a concentration of 2-10 ug/ml. WB: Use at a concentration of 0.5-5 ug/ml. Detects a band of approximately 36 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 1 mg/ml |
| Purity | IgG fraction |
| Buffer | Preservative: NoneConstituents: 50% Glycerol, 0.15M Sodium chloride, 0.02M Sodium phosphate. pH 7.5 |
| Storage | Store at 4C. Aliquot and store at -20C long-term. |
| Restrictions | For research use only |
External Information: alpha SNAP (Human) antibody
| Google Scholar | Find more references for clone 4-00E-004 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen alpha SNAP (Bioinformatic Harvester (EMBL)) |
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