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Product details for alpha Sodium Potassium ATPase (Human) antibody
alpha Sodium Potassium ATPase (Human) antibody
Overview
| Antigen: | Alpha Sodium Potassium ATPase |
| Antibody Type: | Monoclonal |
| Application: | ELISA, Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Rat, Dog (Canine), Bovine |
| Host: | Mouse |
| Quantity: | |
| Price: | 388,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN145626 |
| Availability: | 7 to 10 days until shipment |
Additional Information: alpha Sodium Potassium ATPase (Human) antibody
| Antigen | Alpha Sodium Potassium ATPase |
| Immunogen | Purified sheep kidney alpha sodium / potassium ATPase |
| Reactivity | Human, Rat, Dog (Canine), Bovine |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | The sodium / potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium / potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium / potassium ATPase exhibit tissue-specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a mor |
| Clone | M7-PB-E9 |
| Host | Mouse |
| Specificity | Detects sodium / potassium ATPase alpha.This antibody detects the alpha 3 isoform in rat only. |
Application Details: alpha Sodium Potassium ATPase (Human) antibody
| Application | ELISA, Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | Immunohistochemistry: use at a dilution of 1/100. Western Blot: use at a dilution of 1/250. ELISA: Assay dependent. Immunoprecipitation: Assay dependent. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects an ~110 kDa protein representing alpha sodium / potassium ATPase from MDCK cell extract. Immunohistochemical staining of alpha sodium / potassium ATPase in porcine heart yields a pattern consistent with the plasma membrane localization. |
| Purity | Ascites |
| Buffer | PBS with 0.05% sodium azide |
| Storage | Aliquot and store at -20 C. Avoid repeated freeze / thaw cycles. |
| Restrictions | For research use only |
External Information: alpha Sodium Potassium ATPase (Human) antibody
| Google Scholar | Find more references for clone M7-PB-E9 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen alpha Sodium Potassium ATPase (Bioinformatic Harvester (EMBL)) |
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