Product details for  c-erbB-2 pTyr1248 (Human) antibody
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c-erbB-2 pTyr1248 (Human) antibody

Overview

Antigen: C-erbB-3 / Her-3 C-term
Antibody Type: Monoclonal
Application: Enzyme Immunoassay (EIA), Western Blotting (WB)
Reactivity: Human
Host: Mouse
Quantity: 0.1 mg
Price: 330,00 €   (Plus shipping costs and VAT)
Order number: ABIN126793
Availability: 3 to 10 days until shipment
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Additional Information:  c-erbB-2 pTyr1248 (Human) antibody

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Antigen C-erbB-3 / Her-3 C-term
Immunogen Synthetic petide conjugated to KLH.
Reactivity Human
Antibody Type Monoclonal
Format Purified
Isotype IgG1 »Matching secondary antibodies
Description Molecular weight of antigen is 185kDa.
Clone 11A4
Host Mouse
Specificity ErbB3 is a member of the EGFR/erbB receptor tyrosine kinase family. ErbB3 lacks kinase activity due to an amino acid substitution within the ATP binding site. Upon heterodimerization with the other erbB family members, erbB3 becomes phosphorylated at multiple tyrosine residues that represent docking sites for downstream signaling proteins. This antibody specifically recognizes the C-terminus of erbB3 at 185 kDa in Westen blot and is also suitable for ELISA applications. Epitope: C-Terminus. Reacts with human.

Application Details:  c-erbB-2 pTyr1248 (Human) antibody

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Application Enzyme Immunoassay (EIA), Western Blotting (WB)
Application Notes Western Blot: 0.5 µg/ml for HRPO/ECL detection. Recommended blocking buffer CPPT: 0.5% (w/v) casein, 1% (w/v) PEG 4000, 1% (w/v) Polyvinylpyrrolidone (PVP), 0.1% (v/v) Tween 20, 2x PBS. ELISA: 0.1 µg/ml. Positive control: SW620 untreated. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Format Purified
Buffer This purified antibody lyophilized from 1 ml 2 x PBS / 0.09 % Na-azide / PEG and Sucrose. Reconstitute with 1 ml H2O (15 min, RT).
Storage For long-term storage, freeze lyophilizate upon arrival (-20°C). Upon reconstitution, aliquote and freeze in liquid nitrogen, reconstituted antibody can be stored frozen at -80°C up to 1 year. Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months. Avoid repeated freeze-thaw cycles. Shelf life: one year from despatch.
Research Area Receptors, Growth Factors
Restrictions For Research Use only

External Information:  c-erbB-2 pTyr1248 (Human) antibody

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Google Scholar Find more references for clone 11A4 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen c-erbB-3 / Her-3 C-term (Bioinformatic Harvester (EMBL))