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Product details for l Afadin (Human) antibody
l Afadin (Human) antibody
Overview
| Antigen: | L Afadin |
| Antibody Type: | Polyclonal |
| Application: | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat, Dog (Canine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 310,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN149450 |
| Availability: | 7 to 10 days until shipment |
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Additional Information: l Afadin (Human) antibody
| Antigen | L Afadin |
| Immunogen | Synthetic peptide conjugated to maleimide-activated KLH, corresponding to amino acids 1814-1829 of Rat I Afadin with N-terminal cysteine. |
| Reactivity | Human, Mouse (Murine), Rat, Dog (Canine) |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | Afadin is a cell-cell adherens junction F-actin binding multidomain protein. Two splice variants of afadin have been described: l-afadin, which is ubiquitously expressed, and the smaller s-afadin, which is abundantly expressed in neural tissue. l-Afadin contains one PDZ domain near its middle followed by three proline-rich and one F-actin-binding region at the carboxyl-terminal. l/s-Afadin is localized to cell-cell junctions and binds several cytoplasmic proteins such as the small GTPase Ras, the tight junction protein ZO-1, and the vinculin binding protein ponsin/SH3P12. |
| Host | Rabbit |
Application Details: l Afadin (Human) antibody
| Application | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB) |
| Application Notes | IF: Use at a dilution of 1/500-1/1000. IHC: Use at an assay dependent dilution. WB: Use at a dilution of 1/2000. Detects a band of approximately 200 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.9 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 15mM Sodium AzideConstituents: 1% BSA, 0.01M PBS. pH 7.4 |
| Restrictions | For research use only |
External Information: l Afadin (Human) antibody
| Google Scholar | Find more references for antigen l Afadin on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen l Afadin (Bioinformatic Harvester (EMBL)) |
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