p114RhoGEF (Human) antibody

Overview

Antigen	P114RhoGEF
Immunogen	Synthetic peptide: SAKEDASKEDVIFF.
Reactivity	Human
Antibody Type	Polyclonal
Format	Liquid
Isotype	IgG »Matching secondary antibodies
Description	Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription and cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RhoGEF is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain.
Host	Goat

Application Notes	Peptide ELISA: antibody detection limit dilution 1/4000. Western Blot: Preliminary experiments gave no signal but low background in muman muscle and HepG2 extracts at up to 1.5ug/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration	0.5 mg/ml
Purity	Immunogen affinity purified
Buffer	Preservative: 0.02% Sodium AzideConstituents: 0.5% BSA, Tris-saline. pH 7.3
Restrictions	For research use only

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