p130/Rb2 (Human) antibody

Overview

Antigen	P130/Rb2
Immunogen	A synthetic peptide from p130 corresponding to aa878-913
Reactivity	Human
Antibody Type	Monoclonal
Format	Concentrated
Isotype	IgG1 »Matching secondary antibodies
Description	""" Two retinoblastoma-related proteins, p107 and pRb2/p130, which are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105), were cloned by taking advantage of their ability to bind transforming proteins of DNA tumor viruses through a particular region called the """"""""""""""""pocket domain."""""""""""""""" Like pRb, both proteins play a fundamental role in growth control. These Rb family proteins were measured in a variety of lung neoplasms. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role forThis protein in the pathogenesis and progression of lung cancer."""""""""
Clone	130P211 (same as DCS211)
Host	Mouse

Application	Immunofluorescence (IF)
Application Notes	Immunofluorescence. Optimal dilution should be determined by researcher.
Concentration	0.2 mg/ml
Buffer	200ug/ml of antibody purified from ascites fluid by Protein G chromatography. Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 15mM sodium azide. Also available without BSA and azide at 1mg/ml.
Storage	Store at 4 C. Do not freeze.
Restrictions	For research use only

Google Scholar	Find more references for clone 130P211 (same as DCS211) on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen p130/Rb2 (Bioinformatic Harvester (EMBL))