Quantity: 100 µg. Clone: ARF 4C6-4. Format: Liquid. Description: The INK4a locus on chromosome 9p21 is frequently affected in human tumors. It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse). These two proteins interact with the upst... Immunogen: His-tagged p14ARF protein expr...  More »

Quantity: 500 µl. Format: Liquid. Description: P14 ARF arrests the cell cycle in a p53-dependent manner. p14 ARF binds to mdm 2 and promotes the rapid degradation of mdm 2 protein required for mdm 2 modification and concurrent p53 stabilization and accumulation. This interaction is mediated by the exon 1 beta-encoded N-t... Immunogen: Synthetic peptide correspondin...  More »

Quantity: 100 µg. Format: Liquid. Description: The INK4a locus on chromosome 9p21 is frequently affected in human tumors. It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse). These two proteins interact with the upst... Immunogen: Synthetic peptide: RRACGPPRVRV...  More »

Quantity: 0.1 mg. Format: Aff - Purified. Description: Synonyms: ARF antibody, CDK4 inhibitor p16INK4 antibody, CDK4I antibody, CDKN2 antibody,CDKN2A antibody, Cell cycle negative regulator beta antibody, CMM2 antibody, Cyclindependent kinase inhibitor 2A antibody, Cyclin dependent kinase inhibitor p16 antibody,INK4 antibody, IN... Immunogen: Synthetic peptide: GRCVGPSLQLR... Specificity: Cross-reacts with Human, Mouse and Rat.Not yet tes...  More »

Quantity: 0.1 mg. Format: Aff - Purified. Description: Synonyms: ARF antibody, CDK4 inhibitor p16INK4 antibody, CDK4I antibody, CDKN2 antibody,CDKN2A antibody, Cell cycle negative regulator beta antibody, CMM2 antibody, Cyclindependent kinase inhibitor 2A antibody, Cyclin dependent kinase inhibitor p16 antibody,INK4 antibody, IN... Immunogen: Synthetic peptide: QRLGQQPLPRR... Specificity: Cross-reacts with Human, Mouse and Rat.Not yet tes...  More »

Quantity: 1ml. Description: Ig Fraction, Aff.Pur.  More »

Quantity: 10 µg/50 µl. Clone: DCS-240. Description: P14 ARF is a human tumor suppressor protein associated with the CDK4/pRB and p53 pathways. p14 ARF acts by inhibiting cyclin-dependent kinases, and it can induce both G1 and G2 arrest via its stabilizing effects on the p53 transcription factor. p14 ARF and its mouse homologu... Immunogen: This antibody was purified fro... Specificity: This antibody reacts with human p14 ARF .  More »

Quantity: 500ul. Clone: DCS-240. Immunogen: Purified recombinant prokaryot... Specificity: The INK4a-ARF locus encodes two unrelated proteins...  More »