Product details for  CD86 (Human) antibody
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CD86 (Human) antibody

Overview

Antigen: CD86
Antibody Type: Monoclonal
Application: Flow Cytometry (FACS), Immunohistochemistry ((Frozen Sections) (IHC) (fro))
Reactivity: Human
Host: Mouse
Quantity: 100 µg (0.5 mg/ml)
Price: 247,00 €   (Plus shipping costs and VAT)
Order number: ABIN145179
Availability: 7 to 10 days until shipment
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Additional Information:  CD86 (Human) antibody

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Antigen CD86
Immunogen Recombinant fragment (Human) (extracellular).
Reactivity Human
Antibody Type Monoclonal
Format Liquid
Isotype IgG2a »Matching secondary antibodies
Description CD86 is one of two ligands (the other is CD80) for CD152 (CTLA4) and CD28. CD86 acts as co-stimulatory molecule in eliciting T cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD86 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is rapidly induced on the surface of activated B cells, T cells or monocytes and is expressed at high levels on dendritic cells. It is also found on malignant Hodgkin and Reed-Sternberg (H-RS) cells in Hodgkins disease.
Clone B72-H2
Host Mouse
Specificity Monoclonal Anti-Human CD86 recognizes the extracellular domain of human CD86. It does not detect the extracellular domain of CD80.

Application Details:  CD86 (Human) antibody

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Application Flow Cytometry (FACS), Immunohistochemistry ((Frozen Sections) (IHC) (fro))
Application Notes FACS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration 0.5 mg/ml
Purity Protein G purified
Buffer Preservative: 0.08% Sodium AzideConstituents: 0.01M PBS. pH 7.4
Restrictions For research use only

External Information:  CD86 (Human) antibody

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Google Scholar Find more references for clone B72-H2 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen CD86 (Bioinformatic Harvester (EMBL))