Thrombin Receptor antibody

Overview

Antigen:	Thrombin Receptor
Antibody Type:	Monoclonal
Application:	Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
Host:	Mouse
Quantity:	0.2mg (0.2mg/ml (prior to lyophilizat...)
Price:	483,00 € (Plus shipping costs and VAT)
Order number:	ABIN236474
Availability:	3-5 Business Days

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Additional Information: Thrombin Receptor antibody

Antigen	Thrombin Receptor
Immunogen	N-terminal peptide of thrombin receptor residues 51-64 (KYEPFWEDEEKNES)
Antibody Type	Monoclonal
Format	Purified, Lyophilized
Isotype	IgG1 »Matching secondary antibodies
Description	MAb to Thrombin Receptor Monoclonal Antibody to Thrombin Receptor
Clone	B825M
Host	Mouse
Specificity	Recognizes an epitope on the receptor, distant from the N-terminal thrombin cleavage site (WEDEE). It reacts with both intact and cleaved receptors.

Application Details: Thrombin Receptor antibody

Application	Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
Application Notes	Reconstitution: Reconstitute with 1ml distilled water.
Concentration	0.2mg/ml (prior to lyophilization)
Purification	Protein A chromatography
Buffer	Lyophilized from PBS containing 1mg/ml BSA Preservative: None
Storage	Store lyophilized product at 2-8°C. After reconstitution, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage (up to one month) at 2-8°C. .
Research Area	Coagulation
Restrictions	For Research Use Only

Publications: Thrombin Receptor antibody

Publications

Brass, Vassallo, Belmonte et al.:
"Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defined domain within the receptor N terminus."
In: The Journal of biological chemistry , Vol. 267, Issue 20, pp. 13795-8, 1992/01 (PubMed)

Hoxie, Ahuja, Belmonte et al.:
"Internalization and recycling of activated thrombin receptors."
In: The Journal of biological chemistry , Vol. 268, Issue 18, pp. 13756-63, 1993/01 (PubMed)

Molino, Blanchard, Belmonte et al.:
"Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G."
In: The Journal of biological chemistry , Vol. 270, Issue 19, pp. 11168-75, 1995/01 (PubMed)

Vu, Hung, Wheaton et al.:
"Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation."
In: Cell , Vol. 64, Issue 6, pp. 1057-68, 1991/01 (PubMed)

Woolkalis, DeMelfi, Blanchard et al.:
"Regulation of thrombin receptors on human umbilical vein endothelial cells."
In: The Journal of biological chemistry , Vol. 270, Issue 17, pp. 9868-75, 1995/01 (PubMed)

External Information: Thrombin Receptor antibody

Google Scholar	Find more references for clone B825M on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen Thrombin Receptor (Bioinformatic Harvester (EMBL))