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Product details for MMP2 (Human) antibody
MMP2 (Human) antibody
Overview
| Antigen: | MMP2 |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Mouse |
| Quantity: | |
| Price: | 318,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN145704 |
| Availability: | 7 to 10 days until shipment |
Additional Information: MMP2 (Human) antibody
| Antigen | MMP2 |
| Immunogen | N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV. |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2, also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form of 62kDa. |
| Clone | CA-4001-CA719E3C |
| Host | Mouse |
Application Details: MMP2 (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | Western Blotting: use at a concentration of 0.5-1.0ug / ml for 2hrs at RT. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 2-4ug / ml for 30 min at RT. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 72 kDa (pro form), which corresponds to the predicted molecular weight of MMP-2. No special pretreatment is required for the staining of formalin-fixed, paraffin-embedded tissues |
| Concentration | 0.2 mg/ml |
| Purity | Protein G purified |
| Buffer | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
| Storage | Refrigerate at 4 C. Do not freeze. |
| Restrictions | For research use only |
External Information: MMP2 (Human) antibody
| Google Scholar | Find more references for clone CA-4001-CA719E3C on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen MMP2 (Bioinformatic Harvester (EMBL)) |
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