Product details for  Androgen Receptor (Human) antibody
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Androgen Receptor (Human) antibody

Overview

Antigen: Androgen Receptor
Antibody Type: Monoclonal
Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Reactivity: Human
Host: Mouse
Quantity: 1 ml
Price: 320,00 €   (Plus shipping costs and VAT)
Order number: ABIN112194
Availability: 3 to 10 days until shipment
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Additional Information:  Androgen Receptor (Human) antibody

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Antigen Androgen Receptor
Immunogen Synthetic peptide (aa 301-320 of human AR)
Reactivity Human
Antibody Type Monoclonal
Format Supernatant
Isotype IgG1 »Matching secondary antibodies
Clone F39-4
Host Mouse
Specificity The antibody is reactive with a 110 kD protein in a lysate from the LNCP cell line. The androgen receptor (AR) has been localized e.g. in the testis, (Sertoli and Leydig cells), prostate, foreskin epidermis, fibroblasts, breast epithelium, sweat and apocrine glands and hepatocytes. Prostate cancers are very heterogeneous with regard to AR expression, the loss of androgen responsiveness is not paralleled by the loss of AR. Studies on AR distribution might be useful to study the role of AR in related disease processes. Antigen localization is nuclear. Positive Control: Testis .

Application Details:  Androgen Receptor (Human) antibody

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Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Application Notes Immunohistochemistry on frozen and paraffin embedded sections (microwave pretreatment): 1/5-1/10. Western blotting. Immunocytochemistry. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Buffer This antibody is supplied as liquid, purified Ig fraction containing 0.09% Sodium azide as preservative. Dilute immediately before use with PBS.
Storage Store the antibody at 4-8°C for one month or at –20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Hormones, Receptors
Restrictions For Research Use only

Publications:  Androgen Receptor (Human) antibody

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Publications Zegers, Claassen, Neelen et al.:
"Epitope prediction and confirmation for the human androgen receptor: generation of monoclonal antibodies for multi-assay performance following the synthetic peptide strategy."
In: Biochimica et biophysica acta , Vol. 1073, Issue 1, pp. 23-32, 1991/01 (PubMed)

External Information:  Androgen Receptor (Human) antibody

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Google Scholar Find more references for clone F39-4 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen Androgen Receptor (Bioinformatic Harvester (EMBL))