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Product details for FADD (Human) antibody
FADD (Human) antibody
Overview
| Antigen: | FADD |
| Antibody Type: | Monoclonal |
| Application: | Dot Blot (Dot), ELISA, Immunoprecipitation (IP) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 271,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN144030 |
| Availability: | 7 to 10 days until shipment |
Additional Information: FADD (Human) antibody
| Antigen | FADD |
| Immunogen | Recombinant full length protein (Human). |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C-terminal death domain that interacts with the Fas receptor death domain. The N-terminus contains a death effectors domain (DED, which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL-induced transcriptional activation of c-fos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK-293 cell line. |
| Clone | FD19 |
| Host | Mouse |
Application Details: FADD (Human) antibody
| Application | Dot Blot (Dot), ELISA, Immunoprecipitation (IP) |
| Application Notes | Dot: Use at a concentration of 0.5-1 ug/ml, determined using total cell extracts of A431 cells. ELISA: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 2 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 15mM Sodium AzideConstituents: 0.01M PBS. pH 7.4 |
| Restrictions | For research use only |
External Information: FADD (Human) antibody
| Google Scholar | Find more references for clone FD19 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen FADD (Bioinformatic Harvester (EMBL)) |
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