Integrin alpha M FITC (Human) antibody

Overview

Antigen	Integrin alpha M
Immunogen	Rheumatoid synovial cells and human monocytes.
Reactivity	Human
Antibody Type	Monoclonal
Format	Purified
Isotype	IgG1 »Matching secondary antibodies
Description	Integrin alpha M/beta 2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR 3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha M/beta 2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Clone	FITC-ICRF44
Host	Mouse
Specificity	Recognises the human CD11b cell surface glycoprotein, a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3.

Application	Flow Cytometry (FACS)
Application Notes	Suggested working dilution for flow cytometry: use 10 ul to label 10^6 cells or 100 ul whole blood.
Conjugate	FITC
Concentration	0.1 mg/ml
Purity	Immunogen affinity purified
Buffer	Preservative: 0.1% Sodium AzideConstituents: 1% BSA, PBS
Storage	Store at 4 C for one month. Aliquot and store at -20 C long-term. Avoid repeated freezing and thawing.
Restrictions	For research use only

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EMBL Harvester	Search human, mouse or rat genome for antigen Integrin alpha M (Bioinformatic Harvester (EMBL))