CD62L FITC (Human) antibody

Overview

Antigen	CD62L
Immunogen	Human PHA-activated peripheral blood mononuclear cells.
Reactivity	Human
Antibody Type	Monoclonal
Format	Liquid
Isotype	IgG2b »Matching secondary antibodies
Description	The human CD62L is a 74-95 kD glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells. It is expressed on bone marrow myeloid progenitor cells, erythroid precursor cells and some thymocytes. It is preferentially localized to the tips of lymphocytes and polymorphonuclear cells microvilli. Bioactive soluble L-Selectin derived from lymphocytes and neutrophils is present in normal and pathological biological fluids.
Clone	FMC-46
Host	Mouse
Specificity	Ab11365 recognizes the human CD62L antigen expressed on neutrophils, monocytes, NK cells, B and certain T lymphocytes.

Application	Flow Cytometry (FACS)
Application Notes	FACS: Use 10ul for 10^6 cells. Can be used for detection and enumeration of CD62L cells in blood and tissues in health and disease. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Conjugate	FITC
Purity	Protein A purified
Buffer	Preservative: 15mM Sodium AzideConstituents: 1% BSA, 0.01M PBS (pH7.4)
Restrictions	For research use only

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EMBL Harvester	Search human, mouse or rat genome for antigen CD62L (Bioinformatic Harvester (EMBL))