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Product details for GFAP-Astrocyte Marker (Human) antibody
GFAP-Astrocyte Marker (Human) antibody
Overview
| Antigen: | GFAP-Astrocyte Marker |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Reactivity: | Human, Rat |
| Host: | Mouse |
| Quantity: | |
| Price: | 271,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN146252 |
| Availability: | 7 to 10 days until shipment |
Additional Information: GFAP-Astrocyte Marker (Human) antibody
| Antigen | GFAP-Astrocyte Marker |
| Immunogen | GFAP isolated from porcine spinal cord. |
| Reactivity | Human, Rat |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily and specifically expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. Neuroblastomas, Schwannomas, as well as extra-CNS tumors are not labeled. Negative staining has been observed with lymphatic tissue, muscle, gastrointestinal tract, liver, kidney, pancreas and bladder. |
| Clone | GA-5 |
| Host | Mouse |
| Specificity | This antibody reacts with human GFAP. It shows no cross-reaction with other intermediate filaments. Anti-GFAP stains astrocytes, ependymal cells and corresponding tumors. |
Application Details: GFAP-Astrocyte Marker (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Application Notes | This antibody is ready to use.For best results use heat mediated antigen retrieval, this can enhance staining if tissues are over-fixed.Do not use enzymatic mediated antigen retrieval. We recommend incubating sections with the antibody for 30-60 minutes at room temperature. |
| Purity | IgG fraction |
| Buffer | PBS pH7.3 with protein carrier and preservative |
| Storage | Store at 4 C. Do not freeze. |
| Restrictions | For research use only |
External Information: GFAP-Astrocyte Marker (Human) antibody
| Google Scholar | Find more references for clone GA-5 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen GFAP-Astrocyte Marker (Bioinformatic Harvester (EMBL)) |
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