Product details for  Pyrralin (Advanced Glycation End Products) antibody
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Pyrralin (Advanced Glycation End Products) antibody

Overview

Antigen: Pyrralin (Advanced Glycation )
Antibody Type: Monoclonal
Application: Immunohistochemistry (IHC), ELISA
Host: Mouse
Quantity: 20 µg (0,25 mg/ml)
Price: 650,00 €   (Plus shipping costs and VAT)
Order number: ABIN93836
Availability: Next day shipping, if stock lasts
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Additional Information:  Pyrralin (Advanced Glycation End Products) antibody

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Antigen Pyrralin (Advanced Glycation )
Immunogen Pyrralin-HSA
Antibody Type Monoclonal
Format Purified
Isotype IgG1 »Matching secondary antibodies
Description Langzeit-Inkubation von Proteinen mit Glukose f? ? Schiffsche Basen und Amadori-Umlagerungsprodukte zu Advanced-Glycation-End Products (AGE), die charakterisiert werden durch Fluoreszenzeigenschaften, braune Farbe, inter- und intramolekulare Quervernetzung. Immunologisch wurde AGE in der menschlichen Linse, in der Niere bei chronischer Nephropathie und Amyloidosis, in Arterienw?en bei Arteriosklerose und im Hirngewebe von Patienten mit Morbus Alzheimer nachgewiesen. Pyrralin ist eines der wichtigsten Maillard-Produkte, die durch eine Reaktion von Glukose mit Aminos?en bei leicht saurem pH-Wert entstehen.
Clone H12
Host Mouse

Application Details:  Pyrralin (Advanced Glycation End Products) antibody

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Application Immunohistochemistry (IHC), ELISA
Application Notes Immunhistochemie (2 µg/ml) oder ELISA (0,1-0,5 µg/ml) Secondary reagents Als Sekund?ystem im ELISA, Western Blot und in der Immunhistochemie empfehlen wir biotinylierte anti-Maus IgG-Antik?r . -20°C References 0,1-1,0 µg/ml ELISA, 2 µg/ml IHC
Concentration 0,25 mg/ml
Buffer Protein G affinit?gereinigter Antik?r aus Ascites in stabilisiertem Puffer, enth? 50% Block Ace? (Casein-haltige L?g, Dainippon Co.) und 0,1% ProClin? (Rohm & Haas) als Bakteriostatikum
Storage -20°C
Restrictions For Research Use only

Publications:  Pyrralin (Advanced Glycation End Products) antibody

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Publications Horiuchi S, Araki N, Morino Y:
"Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. Evidence for the presence of a common structure."
In: J Biol Chem , Vol. 266, Issue 12, pp. 7329-32, 1991/04 (PubMed)

Miyata S, Monnier V:
"Immunohistochemical detection of advanced glycosylation end products in diabetic tissues using monoclonal antibody to pyrraline."
In: J Clin Invest , Vol. 89, Issue 4, pp. 1102-12, 1992/04 (PubMed)

Smith MA, Taneda S, Richey PL et al.:
"Advanced Maillard reaction end products are associated with Alzheimer disease pathology."
In: Proc Natl Acad Sci U S A , Vol. 91, Issue 12, pp. 5710-4, 1994/06 (PubMed)

Odetti P, Angelini G, Dapino D et al.:
"Early glycoxidation damage in brains from Down's syndrome."
In: Biochem Biophys Res Commun , Vol. 243, Issue 3, pp. 849-51, 1998/02 (PubMed)

External Information:  Pyrralin (Advanced Glycation End Products) antibody

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Google Scholar Find more references for clone H12 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen Pyrralin (Advanced Glycation End Products) (Bioinformatic Harvester (EMBL))