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Product details for PKA RII (Human) antibody
PKA RII (Human) antibody
Overview
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| Antigen: | Protein Kinase A (PKA) RII subunit |
| Antibody Type: | Monoclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 330,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN121015 |
| Availability: | Ships in 3 to 10 days |
Additional Information: PKA RII (Human) antibody
| Antigen | Protein Kinase A (PKA) RII subunit |
| Immunogen | Column purified fraction of cAMP dependent PKA RII from human saliva. |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Ascites |
| Isotype | IgG2b »Matching secondary antibodies |
| Clone | H2 006 D4 |
| Host | Mouse |
| Specificity | The type 1(RI) and type 2 (RII) subunit of cyclic AMP-dependent protein kinase A (PKA) is a polyfunctional protein that is present in most tissues and cells. The many roles of RII include: 1) the regulation of extracellular cyclic AMP levels, 2) catalyzing the phosphorylation of the transcription factor CREB, 3) aiding in the development of mammalian oocytes and 4) phosphorylation of proteins to enhance the release of neurotransmitters. Localization of PKA is coordinated through association with A-kinase anchoring proteins (AKAPs) that bind to a 14-18aa sequence in subunit RII. This antibody detects PKA RII protein in human samples. ABIN121015 does not discriminate between RII alpha and beta. |
Application Details: PKA RII (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | Western Blot (1/1000, detects an ~50 kDa protein representing PKA RII in human saliva). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user. |
| Concentration | 10 mg/ml |
| Buffer | This antibody is supplied as liquid, ascites containing 0.05% sodium azide as preservative. |
| Storage | Store the antibody at –20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Research Area | Signaling, Protein Modifications, Kinases/Phosphatases |
| Restrictions | Research only |
Images: PKA RII (Human) antibody
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Figure 1 shows a Western blot of PKA RII in human saliva using ABIN121015. |
External Information: PKA RII (Human) antibody
| Google Scholar | Find more references for clone H2 006 D4 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Protein Kinase A (PKA) RII subunit (Bioinformatic Harvester (EMBL)) |
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