Product details for  ErbB 4 (Human) antibody
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ErbB 4 (Human) antibody

Overview

Antigen: ErbB 4
Antibody Type: Monoclonal
Application: Flow Cytometry (FACS), Functional Studies (FUNC), Immunoprecipitation (IP)
Reactivity: Human, Mouse (Murine), Rat
Host: Mouse
Quantity: 500 µl (0.2 mg/ml)
Price: 271,00 €   (Plus shipping costs and VAT)
Order number: ABIN145730
Availability: 7 to 10 days until shipment
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Additional Information:  ErbB 4 (Human) antibody

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Antigen ErbB 4
Immunogen Extracellular fragment of recombinant human c-erbB-4 / HER 4 oncoprotein.
Reactivity Human, Mouse (Murine), Rat
Antibody Type Monoclonal
Format Liquid
Isotype IgG1 »Matching secondary antibodies
Description C-erbB-4 is the fourth member of class I receptor kinase family (ErbB). Down regulation of ErbB-4 in estrogen receptor-positive cancer cells inhibits proliferation.
Clone H4-77-16
Host Mouse

Application Details:  ErbB 4 (Human) antibody

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Application Flow Cytometry (FACS), Functional Studies (FUNC), Immunoprecipitation (IP)
Application Notes Flow Cytometry: assay dependent. Functional studies (see below): assay dependent. Immunoprecipitation (with protein G): use at a concentration of 2ug/mg of protein lysate. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. This antibody is not suitable for western blot (Tang C, et. al). This antibody does not interfere with receptor-heregulin binding and is particularly wellsuited for immunoprecipitation of unoccupied as wellas the occupied c-erbB-4 receptor (Chen X, et. al.). It reacts withintact cells, stimulates tyrosine kinase activity, andefficiently stimulates internalization of c-erbB-4 (Chen X, et. al.).
Concentration 0.2 mg/ml
Purity Protein G purified
Buffer 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Storage Refrigerate at 4 C. Do not freeze.
Restrictions For research use only

External Information:  ErbB 4 (Human) antibody

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Google Scholar Find more references for clone H4-77-16 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen ErbB 4 (Bioinformatic Harvester (EMBL))