Product details for  C-erbB-4 / Her-4 (Human) antibody
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C-erbB-4 / Her-4 (Human) antibody

Overview

Antigen: C-erbB-4 / Her-4
Antibody Type: Monoclonal
Application: Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Reactivity: Human, Mouse (Murine)
Host: Mouse
Quantity: 0.2 mg (1 mg/ml)
Price: 330,00 €   (Plus shipping costs and VAT)
Order number: ABIN121070
Availability: Ships in 3 to 10 days
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Additional Information:  C-erbB-4 / Her-4 (Human) antibody

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Antigen C-erbB-4 / Her-4
Immunogen Synthetic Peptide: C R(1250) S T L Q H P D Y L Q E Y S T(1264) corresponding to amino acid residues 1250 to 1264 of human Her-4 oncoprotein.
Reactivity Human, Mouse (Murine)
Antibody Type Monoclonal
Format Purified
Isotype IgG2b »Matching secondary antibodies
Clone HRF1
Host Mouse
Specificity Her-4, also known as c-erbB-4 and v-erbB-4, is a Type 1 membrane protein found in numerous cell types. It is a member of the EGF receptor protein family, and is activated by neuregulins and NTAK. Her-4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies. Her-4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself. ABIN121070 detects Her-4 from human and mouse samples.

Application Details:  C-erbB-4 / Her-4 (Human) antibody

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Application Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Application Notes Immunoprecipitation. Immunohistochemistry on paraffin embedded sections (6 – 8 ug/ml, paraffin embedded mouse NIH3T3 cells). Western Blot (3 ug/ml, detects ~185 kDa protein representing Her-4 from human A431 cell and mouse NIH3T3/HER4 cell extracts.). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 1 mg/ml
Buffer This antibody is supplied as liquid, protein A purified IgG in PBS with 1 mg/ml BSA and 0.05% sodium azide as preservative.
Storage Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Receptors, Growth Factors
Restrictions Research only

External Information:  C-erbB-4 / Her-4 (Human) antibody

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Google Scholar Find more references for clone HRF1 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen C-erbB-4 / Her-4 (Bioinformatic Harvester (EMBL))