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Cell Lysis Buffer

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Sample Preparation (Prep)
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Comment

The Cell Lysis Buffer is optimized for lysis of mammalian cells and tissues for caspase activity assays. The buffer is intended to use as a supplemental reagent for researchers who need to lyse large amount of cells or tissues.

Restrictions For Research Use only
Format Liquid
Storage 4 °C
Expiry Date 12 months
Product cited in: Suda, Itoh, Nakato, Shirakawa, Bando, Katou, Kataoka, Shirahige, Tickle, Tanaka: "Dimeric combinations of MafB, cFos and cJun control the apoptosis-survival balance in limb morphogenesis." in: Development (Cambridge, England), Vol. 141, Issue 14, pp. 2885-94, 2014

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Hossain, Richardson: "Mechanism of Pyrethroid Pesticide-Induced Apoptosis: Role of Calpain and the ER Stress Pathway." in: Toxicological sciences : an official journal of the Society of Toxicology, 2011

Rasbach, Funk, Jayavelu, Green, Schnellmann: "5-hydroxytryptamine receptor stimulation of mitochondrial biogenesis." in: The Journal of pharmacology and experimental therapeutics, Vol. 332, Issue 2, pp. 632-9, 2010

Lu, Verma, Murakami, Cai, Kumar, Xiao, Robertson: "Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (KSHV) upregulates survivin expression in KSHV-Associated B-lymphoma cells and contributes to their proliferation." in: Journal of virology, Vol. 83, Issue 14, pp. 7129-41, 2009

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Rasbach, Schnellmann: "Isoflavones promote mitochondrial biogenesis." in: The Journal of pharmacology and experimental therapeutics, Vol. 325, Issue 2, pp. 536-43, 2008

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Mohammad, Goustin, Aboukameel, Chen, Banerjee, Wang, Nikolovska-Coleska, Wang, Al-Katib: "Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 7, pp. 2226-35, 2007

Rasbach, Schnellmann: "Signaling of mitochondrial biogenesis following oxidant injury." in: The Journal of biological chemistry, Vol. 282, Issue 4, pp. 2355-62, 2007

Takayama, Rogatsky, Schwarcz, Darimont: "The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-beta-catenin complex." in: The Journal of biological chemistry, Vol. 281, Issue 26, pp. 17856-63, 2006

Zeitlin, Joo, Dong, Warner, Wang, Nikolovska-Coleska, Wang, Nör: "Antiangiogenic effect of TW37, a small-molecule inhibitor of Bcl-2." in: Cancer research, Vol. 66, Issue 17, pp. 8698-706, 2006

Mohammad, Wang, Aboukameel, Chen, Wu, Chen, Al-Katib: "Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma." in: Molecular cancer therapeutics, Vol. 4, Issue 1, pp. 13-21, 2005

Ray, Akbiyik, Bernstein, Phipps: "CD40 engagement prevents peroxisome proliferator-activated receptor gamma agonist-induced apoptosis of B lymphocytes and B lymphoma cells by an NF-kappaB-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 7, pp. 4060-9, 2005

Yano, Itoh, Kubota, Sendo, Koyama, Fujita, Saeki, Yuo, Oishi: "A prostacyclin analog prevents radiocontrast nephropathy via phosphorylation of cyclic AMP response element binding protein." in: The American journal of pathology, Vol. 166, Issue 5, pp. 1333-42, 2005

Nowak, Price, Schnellmann: "Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells." in: American journal of physiology. Renal physiology, Vol. 285, Issue 3, pp. F440-50, 2003

Cummings, Schnellmann: "Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways." in: The Journal of pharmacology and experimental therapeutics, Vol. 302, Issue 1, pp. 8-17, 2002

Ghatak, Misra, Toole: "Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38013-20, 2002

Nowak: "Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 43377-88, 2002