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anti-Rat (Rattus) Acrosin Antibodies:
anti-Human Acrosin Antibodies:
anti-Mouse (Murine) Acrosin Antibodies:
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Human Polyclonal Acrosin Primary Antibody for IF (p), IHC (p) - ABIN1387665
Liang, Cheng, Jiang, He, Wang, Jiang, Hou, Li, Liu, Wang: The noncircadian function of the circadian Clock gene in the regulation of male fertility. in Journal of biological rhythms 2013
Show all 2 references for 1387665
Human Polyclonal Acrosin Primary Antibody for EIA, IHC (p) - ABIN950252
Dubé, Leclerc, Baba, Reyes-Moreno, Bailey: The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm. in Journal of andrology 2005
Show all 2 references for 950252
Human Polyclonal Acrosin Primary Antibody for EIA, FACS - ABIN950251
Furlong, Veaute, Vazquez-Levin: Binding of recombinant human proacrosin/acrosin to zona pellucida glycoproteins. II. Participation of mannose residues in the interaction. in Fertility and sterility 2005
Show all 2 references for 950251
Human Polyclonal Acrosin Primary Antibody for ICC, IF - ABIN4277740
Reda, Hou, Winton, Chapin, Söder, Stukenborg: In vitro differentiation of rat spermatogonia into round spermatids in tissue culture. in Molecular human reproduction 2016
The present study was aimed at examining the acrosin activity variations in acrosome exocytosis and its regulation by tyrosine kinase (show TYRO3 Antibodies), protein kinase C (show PKC Antibodies) and voltage-dependent calcium channels.
acrosin was isolated from turkey spermatozoa
During epididymal maturation of boar sperm, alpha-/beta-acrosin isoform expression increases, reaching maximum in cauda; gamma-acrosin isoform is not expressed. In vitro capacitation leads to relocation of acrosin to apical ridge of sperm head.
Data indicate that the positive expression of studied genes fertilization rate for GAPDHS (show GAPDHS Antibodies) positive subset was 66%, ACR - 71%, SPATA22 - 68%, MND1 (show MND1 Antibodies) - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively.
Sperm DNA damage is closely related with sperm-nucleoprotein transition, acrosin activity and seminal parameters.
DNA immunization against proacrosin impairs fertility in male mice.
Binding sites for recombinant human zona pellucida (ZP) glycoproteins located at the N- and C-termini of proacrosin reveal a key role of the proenzyme in the interaction.
SERPINA3K is involved in the Clock gene-mediated male fertility by regulating acrosin activity and provide the first evidence that SERPINA3K could be regulated by Clock gene via retinoic acid-related orphan receptor (show NR1D2 Antibodies) response elements.
ACR or PRSS21 (show PRSS21 Antibodies) or both may function cooperatively with SPAM1 (show SPAM1 Antibodies) in sperm/cumulus penetration
These data demonstrate that the trypsinlike protease activity of ACR and PRSS21 (show PRSS21 Antibodies) is essential for the process of sperm penetration through the cumulus matrix and zona pellucida in vitro
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
, acrosin 1
, 53 kDa fucose-binding protein
, acrosin prepropeptide
, acrosin light and heavy chain prepropeptide