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Browse our Acrosin Proteins (ACR)

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Acrosin Proteins (ACR)
On are 11 Acrosin (ACR) Proteins from 5 different suppliers available. Additionally we are shipping Acrosin Antibodies (69) and Acrosin Kits (13) and many more products for this protein. A total of 96 Acrosin products are currently listed.
ACR, Acro, Acrosin, MGC130972
list all proteins Gene Name GeneID UniProt
ACR 24163 P29293
ACR 49 P10323
ACR 11434 P23578

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Acrosin Proteins (ACR) by Origin

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More Proteins for Acrosin Interaction Partners

Cow (Bovine) Acrosin (ACR) interaction partners

  1. The present study was aimed at examining the acrosin activity variations in acrosome exocytosis and its regulation by tyrosine kinase, protein kinase C and voltage-dependent calcium channels.

Turkey Acrosin (ACR) interaction partners

  1. acrosin was isolated from turkey spermatozoa

Pig (Porcine) Acrosin (ACR) interaction partners

  1. During epididymal maturation of boar sperm, alpha-/beta-acrosin isoform expression increases, reaching maximum in cauda; gamma-acrosin isoform is not expressed. In vitro capacitation leads to relocation of acrosin to apical ridge of sperm head.

Human Acrosin (ACR) interaction partners

  1. Data indicate that the positive expression of studied genes fertilization rate for GAPDHS (show GAPDHS Proteins) positive subset was 66%, ACR - 71%, SPATA22 - 68%, MND1 (show MND1 Proteins) - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively.

  2. Sperm DNA damage is closely related with sperm-nucleoprotein transition, acrosin activity and seminal parameters.

  3. DNA immunization against proacrosin impairs fertility in male mice.

  4. Binding sites for recombinant human zona pellucida (ZP) glycoproteins located at the N- and C-termini of proacrosin reveal a key role of the proenzyme in the interaction.

Mouse (Murine) Acrosin (ACR) interaction partners

  1. SERPINA3K (show SERPINA3K Proteins) is involved in the Clock gene-mediated male fertility by regulating acrosin activity and provide the first evidence that SERPINA3K (show SERPINA3K Proteins) could be regulated by Clock gene via retinoic acid-related orphan receptor (show NR1D2 Proteins) response elements.

  2. ACR or PRSS21 (show PRSS21 Proteins) or both may function cooperatively with SPAM1 (show SPAM1 Proteins) in sperm/cumulus penetration

  3. These data demonstrate that the trypsinlike protease activity of ACR and PRSS21 (show PRSS21 Proteins) is essential for the process of sperm penetration through the cumulus matrix and zona pellucida in vitro

Acrosin (ACR) Protein Profile

Protein Summary

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Alternative names and synonyms associated with Acrosin (ACR)

  • acrosin (ACR)
  • acrosin-like (LOC100057028)
  • acrosin (acr)
  • acrosin (Acr)
  • acrosin prepropeptide (Acr)
  • ACR protein
  • Acro protein
  • Acrosin protein
  • MGC130972 protein

Protein level used designations for Acrosin Proteins (ACR)

acrosin , acrosin 1 , proacrosin , 53 kDa fucose-binding protein , preproacrosin , acrosin prepropeptide , acrosin light and heavy chain prepropeptide

606765 Canis lupus familiaris
280711 Bos taurus
100057028 Equus caballus
426864 Gallus gallus
692129 Meleagris gallopavo
458950 Pan troglodytes
716579 Macaca mulatta
734776 Xenopus laevis
397098 Sus scrofa
24163 Rattus norvegicus
100717414 Cavia porcellus
49 Homo sapiens
100009184 Oryctolagus cuniculus
11434 Mus musculus
443195 Ovis aries
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