anti-Human CACNB4 antibody for Western Blotting

Recommended CACNB4 Antibody (supplied by: Log in to see )

Antigen
Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Antibodies
  • CACNB4
  • CAB4
  • CACNLB4
  • EA5
  • EIG9
  • EJM
  • EJM4
  • EJM6
  • 3110038O15Rik
  • Cchb4
  • lethargic
  • lh
  • calcium channel, voltage-dependent, beta 4 subunit
  • CACNB4
  • cacnb4.1
  • cacnb4
  • Cacnb4
Epitope
C-Term
36
29
5
4
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
91
53
52
18
6
5
5
4
4
3
3
3
2
2
2
Host
Rabbit
45
32
18
Clonality
Polyclonal
Conjugate
This CACNB4 antibody is un-conjugated
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
1
1
Application
Western Blotting (WB)
91
42
39
38
37
33
18
3
1
1
1
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Catalog No. ABIN2776098
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN2774681 WB Rabbit Middle Region Log in to see Polyclonal
3.2182703 ABIN188690 ELISA WB Goat C-Term, all Isoforms Log in to see Polyclonal 1
3.2182703 ABIN2485251 AA ICC IF IHC IP WB Atto 565 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485249 AA ICC IF IHC IP WB Atto 390 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485253 AA ICC IF IHC IP WB Atto 633 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485255 AA ICC IF IHC IP WB Atto 680 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485256 AA ICC IF IHC IP WB Atto 700 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485258 AA ICC IF IHC IP WB APC Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485259 AA ICC IF IHC IP WB Biotin Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485260 AA ICC IF IHC IP WB FITC Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485252 AA ICC IF IHC IP WB Atto 594 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485257 AA ICC IF IHC IP WB Alkaline Phosphatase (AP) Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485261 AA ICC IF IHC IP WB HRP Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485263 AA ICC IF IHC IP WB PerCP Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485262 AA ICC IF IHC IP WB PE-Atto 594 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485265 AA ICC IF IHC IP WB Streptavidin Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485250 AA ICC IF IHC IP WB Atto 488 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485254 AA ICC IF IHC IP WB Atto 655 Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN2485264 AA ICC IF IHC IP WB PE Mouse IgG1 AA 458-474 Log in to see S10-7 1
3.2182703 ABIN4286786 ELISA WB Goat C-Term Log in to see Polyclonal 1

General

Antigen Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Antibodies
Epitope C-Term
(36), (29), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
(91), (53), (52), (18), (6), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2)
Host Rabbit
(45), (32), (18)
Clonality
Polyclonal
Conjugate This CACNB4 antibody is un-conjugated
(4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Western Blotting (WB)
(91), (42), (39), (38), (37), (33), (18), (3), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CACNB4 Antibody

Target Details CACNB4 Application Details Handling References for anti-CACNB4 antibody (ABIN2776098) Images
Blocking Peptide Blocking peptide for this product available: ABIN974380
Sequence LEAYWRATHT TSSTPMTPLL GRNLGSTALS PYPTAISGLQ SQRMRHSNHS
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against CACNB4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CACNB4

Target Details CACNB4

Product Details anti-CACNB4 Antibody Application Details Handling References for anti-CACNB4 antibody (ABIN2776098) Images back to top
Antigen
Alternative Name CACNB4 (CACNB4 Antibody Abstract)
Background CACNB4 is a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Alias Symbols: CAB4, CACNLB4, EA5, EJM, EIG9, EJM4, EJM6
Protein Interaction Partner: CBX3, FASLG, REM1, MED31, TBL3, CACNA1A, PTN,
Protein Size: 486
Molecular Weight 55 kDa
Gene ID 785
NCBI Accession NM_001005747, NP_001005747
Research Area Signaling
Pathways cAMP Metabolic Process, Skeletal Muscle Fiber Development

Application Details

Product Details anti-CACNB4 Antibody Target Details CACNB4 Handling References for anti-CACNB4 antibody (ABIN2776098) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 486 AA

Restrictions For Research Use only

Handling

Product Details anti-CACNB4 Antibody Target Details CACNB4 Application Details References for anti-CACNB4 antibody (ABIN2776098) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CACNB4 antibody (ABIN2776098)

Product Details anti-CACNB4 Antibody Target Details CACNB4 Application Details Handling Images back to top
Background publications

Kobayashi, Yamada, Fukao, Shiratori, Tsutsuura, Tanimoto, Tohse: "The GK domain of the voltage-dependent calcium channel beta subunit is essential for binding to the alpha subunit." in: Biochemical and biophysical research communications, Vol. 360, Issue 3, pp. 679-83, 2007

Suzuki, Yamashita, Shirota, Sakakibara, Chiba, Mizushima-Sugano, Nakai, Sugano: "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions." in: Genome research, Vol. 14, Issue 9, pp. 1711-8, 2004

Images

Product Details anti-CACNB4 Antibody Target Details CACNB4 Application Details Handling References for anti-CACNB4 antibody (ABIN2776098) back to top
Supplier Images
Western Blotting (WB) image for anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (C-Term) antibody (ABIN2776098) WB Suggested Anti-CACNB4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (C-Term) antibody (ABIN2776098) WB Suggested Anti-CACNB4
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500 ...