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anti-Human GALR3 Antibodies:
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Human Polyclonal GALR3 Primary Antibody for EIA, WB - ABIN952454
Belfer, Hipp, Bollettino, McKnight, Evans, Virkkunen, Albaugh, Max, Goldman, Enoch: Alcoholism is associated with GALR3 but not two other galanin receptor genes. in Genes, brain, and behavior 2007
Show all 5 references for 952454
Human Polyclonal GALR3 Primary Antibody for IHC, ELISA - ABIN185603
Swanson, Blackburn, Zhang, Zheng, Xu, Hökfelt, Wolinsky, Konkel, Chen, Zhong, Walker, Craig, Gerald, Branchek: Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. in Proceedings of the National Academy of Sciences of the United States of America 2005
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Data from ligand-receptor interaction studies suggest that human spexin (show C12orf39 Antibodies)-1 and zebrafish spexin (show C12orf39 Antibodies)-2 activate galanin (show GAL Antibodies) receptors GALR2 (show GALR2 Antibodies)/GALR3 (but not GALR1 (show GALR1 Antibodies)); thus spexins appear to be natural ligands for human/Xenopus/zebrafish GALR2 (show GALR2 Antibodies)/GALR3.
Variants in genes for galanin (GAL (show GAL Antibodies)) and its receptors (GALR1 (show GALR1 Antibodies), GALR2 (show GALR2 Antibodies), GALR3), despite their disparate genomic loci, conferred increased risk of depression and anxiety in people who experienced childhood adversity or recent negative life events.
The results suggest that GalR3, a receptor for the neuroendocrine peptide galanin (show GAL Antibodies), is a potential marker for relapsing pituitary tumors.
Mutated human GalR3 receptors are tested with competitive binding analysis in vitro, identifying six different sites in GalR3 that determine binding to galanin (show GAL Antibodies).
Elevated expression of galanin (show GAL Antibodies) receptors in childhood neuroblastic tumors.
GALR3 showed a significant association with alcoholism that was driven by one SNP (rs3,091,367).
After arthritis induction, GAL3 (show LGALS3 Antibodies) knockouts demonstrated increased clinical disease severity and earlier hindlimb edema than wild types.
Our data suggest involvement of GAL3 (show LGALS3 Antibodies) receptors in GAL (show GAL Antibodies)-mediated effects on mood, anxiety, and behavior.
This study shows GalR3-mediated neuroprotection, supporting a potential future therapeutic development, based on GalR3 activation, for the treatment of brain disorders
Data show that galanin (show GAL Antibodies) receptor mRNA and protein are expressed in mouse pancreas, with GALR3 mRNA predominating.
GalR3 is the receptor subtype mediating galanin's effects on the dermal microvasculature
Receptor for the hormone galanin.
galanin receptor type 3
, galanin receptor 3
, galanin receptor, family member 3