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Browse our anti-PKD2 (PKD2) Antibodies

Full name:
anti-Protein Kinase D2 Antibodies (PKD2)
On www.antibodies-online.com are 123 Protein Kinase D2 (PKD2) Antibodies from 15 different suppliers available. Additionally we are shipping PKD2 Proteins (11) and PKD2 Kits (8) and many more products for this protein. A total of 150 PKD2 products are currently listed.
Synonyms:
AI325941, APKD2, nPKC-D2, Pc-2, PC2, PKD2, PKD4, PRKD2, RGD1308054, TRPP2

Most Popular Reactivities for anti-PKD2 (PKD2) Antibodies

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anti-Human PKD2 Antibodies:

anti-Mouse (Murine) PKD2 Antibodies:

anti-Rat (Rattus) PKD2 Antibodies:

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Top referenced anti-PKD2 Antibodies

  1. Human Polyclonal PKD2 Primary Antibody for IP, WB - ABIN152061 : Liu, Evans, Britton, Zachary: The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis. in Oncogene 2008 (PubMed)
    Show all 8 references for ABIN152061

  2. Human Polyclonal PKD2 Primary Antibody for EIA, IHC (p) - ABIN360330 : Stayner, Zhou: Polycystin channels and kidney disease. in Trends in pharmacological sciences 2001 (PubMed)
    Show all 5 references for ABIN360330

More Antibodies against PKD2 Interaction Partners

Human Protein Kinase D2 (PKD2) interaction partners

  1. SNPs in and near PKD2 showed significant evidence of association in individual samples of black adults (rs17013735, P-value=0.0009) and white adults (rs11938025; P-value=0.0005; rs2725270, P-value=0.003).

  2. Pancreatic cysts were more prevalent in patients with ADPKD with PKD2 mutation than in control subjects or patients with PKD1 (show PKD1 Antibodies) mutation.

  3. This study discovered and characterized a novel, highly conserved N-terminal domain, comprising 92 amino acids, which mediates dimerization of Protein Kinase D (PKD) isoforms, PKD1 (show PKD1 Antibodies), PKD2, and PKD3 (show PRKD3 Antibodies) monomers.

  4. This suggests that a precise dosage of PC2 (show KRT6B Antibodies) is necessary for an adequate mechanosensitive alpha-actinin (show ACTN1 Antibodies) recruitment at junctions.

  5. PKD1 (show PKD1 Antibodies) and PKD2 are susceptibility genes for familial intracranial aneurysms in a Japanese population.

  6. Novel PKD2 mutations in Chinese autosomal dominant polycystic kidney disease patients

  7. Two neutral missense PKD2 variants indentified in exon1 c.83G>C (p.R28P) and c.568G>A (p.A190T), which the former segregate with the mutation in affected relatives, and two new intronic and 3'UTR (show UTS2R Antibodies) variants, c.1548+63C>T and c.*363delA.

  8. this study presents the cryo-EM structure of PKD2 in lipid bilayers at 3.0 A resolution, which establishes PKD2 as a homotetrameric ion channel and provides insight into potential mechanisms for its activation.

  9. PCs expression and p53 (show TP53 Antibodies) activation as a regulator of cell proliferation were further evaluated in vivo and in 69 advanced human carotid atherosclerotic plaques.

  10. PKD2 and RSK1 (show RPS6KA1 Antibodies) regulate integrin beta4 phosphorylation at threonine 1736 to stabilize keratinocyte cell adhesion and its hemidesmosomes.

Mouse (Murine) Protein Kinase D2 (PKD2) interaction partners

  1. Our studies demonstrate that PKD1 (show PKD1 Antibodies)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (show DGKA Antibodies) effect on MVB secretory traffic.

  2. Results reveal that whereas protein kinase D1 (show PRKD1 Antibodies) and protein kinase D2 are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  3. PKD2 acted as an amplification checkpoint for antigen-stimulated digital cytokine responses and translated the differential strength of TCR signaling to determine the number of naive CD8 (show CD8A Antibodies)(+) T cells that became effector cells.

  4. Protein kinase D2 promotes in vitro osteoclast differentiation and fusion

  5. A bioinformatic screen identified the serine-threonine kinase (show CDK4 Antibodies) protein kinase D2 (PRKD2) as a potential effector of GABP in hematopoietic stem cells

  6. Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by alpha/beta mature TCR complexes in peripheral T-cells.

  7. PKD2 is a common signaling target downstream of various agonist receptors in platelets and G(q)-mediated signals along with calcium and novel PKC (show PKC Antibodies) isoforms, in particular, PKCdelta (show PKCd Antibodies) activate PKD2 in platelets.

  8. Data demonstrate that, unlike PKD1 (show PKD1 Antibodies), PKD2 catalytic activity is dispensable for normal embryogenesis.

  9. PKD2, like PKD (show PRKD1 Antibodies), facilitates mitogenesis in 3T3 cells

PKD2 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PKD2

  • protein kinase D2 (PRKD2) antibody
  • polycystic kidney disease 2 (autosomal dominant) (PKD2) antibody
  • protein kinase D2 (Prkd2) antibody
  • AI325941 antibody
  • APKD2 antibody
  • nPKC-D2 antibody
  • Pc-2 antibody
  • PC2 antibody
  • PKD2 antibody
  • PKD4 antibody
  • PRKD2 antibody
  • RGD1308054 antibody
  • TRPP2 antibody

Protein level used designations for PKD2

protein kinase D2 , serine/threonine-protein kinase D2-like , R48321 , autosomal dominant polycystic kidney disease type II protein , polycystin-2 , polycystwin , transient receptor potential cation channel, subfamily P, member 2 , serine/threonine-protein kinase D2 , nPKC-D2

GENE ID SPECIES
468929 Pan troglodytes
782793 Bos taurus
100407181 Callithrix jacchus
100471375 Ailuropoda melanoleuca
5311 Homo sapiens
25865 Homo sapiens
101540 Mus musculus
292658 Rattus norvegicus
484427 Canis lupus familiaris
100517036 Sus scrofa
100355908 Oryctolagus cuniculus
100717067 Cavia porcellus
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