Browse our Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) ELISA Kits

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Rap Guanine Nucleotide Exchange Factor (GEF) 3 ELISA Kits (RAPGEF3)
On www.antibodies-online.com are 0 Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) ELISA Kits from different suppliers available. Additionally we are shipping Rap Guanine Nucleotide Exchange Factor (GEF) 3 Antibodies (66) and Rap Guanine Nucleotide Exchange Factor (GEF) 3 Proteins (8) and many more products for this protein. A total of 86 Rap Guanine Nucleotide Exchange Factor (GEF) 3 products are currently listed.
Synonyms:
2310016P22Rik, 9330170P05Rik, bcm910, CAMP-GEFI, Epac, Epac1, HSU79275, RAPGEF3, si:dkey-27m20.2
list all ELISA KIts Gene Name GeneID UniProt
Human RAPGEF3 RAPGEF3 10411 O95398
Mouse RAPGEF3 RAPGEF3 223864 Q8VCC8
Rat RAPGEF3 RAPGEF3 59326 Q9Z1C8

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More ELISA Kits for Rap Guanine Nucleotide Exchange Factor (GEF) 3 Interaction Partners

Cow (Bovine) Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. prostacyclin regulates bone growth via the Epac/Rap1 pathway

Xenopus laevis Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. cAMP binds Xepac protein enabling it to activate the Ca2 (show CA2 ELISA Kits)+ pathway, which is necessary to start and maintain X. laevis vitellogenin (show VTG ELISA Kits) uptake.

Human Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. This review focus is on the function of Epac in the heart. Accumulating evidence has revealed that both Epac1 and Epac2 (show RAPGEF4 ELISA Kits) play important roles in the structure and function of the heart under physiological and pathological conditions. [review]

  2. This interaction is promoted by EPAC1 activation, triggering its translocation to the plasma membrane and binding to NHERF1 (show SLC9A3R1 ELISA Kits). Our findings identify a new CFTR (show CFTR ELISA Kits)-interacting protein and demonstrate that cAMP activates CFTR (show CFTR ELISA Kits) through two different but complementary pathways - the well-known PKA-dependent channel gating pathway and a new mechanism regulating endocytosis that involves EPAC1.

  3. The contribution of EGFR (show EGFR ELISA Kits), EPAC, and Ca(2 (show CA2 ELISA Kits)+) in CDCA-induced activation of CFTR (show CFTR ELISA Kits)-dependent Cl(-) secretion.

  4. Microtubule stabilization was further suggested by the finding that ascorbate increased the amount of Epac1 bound to alpha-tubulin (show TUBA4A ELISA Kits).

  5. during Epac1-induced activation of mTORC1 and mTORC2 (show CRTC2 ELISA Kits), Epac1 may have an additional function as a scaffold protein (show HOMER1 ELISA Kits)

  6. The overexpression of EPAC1 can be used as a marker to predict the outcome of patients with GC, and EPAC1 represents a potential therapeutic modality for treating gastric cancer

  7. our data provide new insight into the essential role of Epac1 in regulating growth of ovarian cancer cells and suggest that Epac1 might represent an attractive therapeutic target for treatment of ovarian cancer.

  8. These findings suggested Epac is connected to the SDF-1 (show CXCL12 ELISA Kits) signaling cascades. In conclusion, our study revealed that Epac plays a role in human mesenchymal stem cells (hMSCs)homing by promoting adhesion and migration. Appropriate manipulation of Epac may enhance the homing of hMSCs and facilitate their future clinical applications.

  9. EPAC activity is increased in arterial endothelial cells exposed to laminar-fluid shear stress, activation of EPAC1, and its activation of Rap1, plays a role in promoting alignment and elongation of these cells in the direction of flow.

  10. EPAC activation consistently reverses clinical and experimental impairment of neutrophil phagocytosis. EPAC signals through Rap-1 (show RABGEF1 ELISA Kits) and bypasses RhoA (show RHOA ELISA Kits). EPAC activation represents a novel potential means by which to reverse impaired neutrophil phagocytosis.

Mouse (Murine) Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. 2-arachidonoylglycerol (2-AG) is an endogenous cannabinoid that depresses synaptic transmission through stimulation of CB1 (show CNR1 ELISA Kits) receptors. Among the six isoforms of phospholipase C (PLC (show PLC ELISA Kits); PLCbeta, PLCgamma, PLCdelta, PLCepsilon (show PLCE1 ELISA Kits), PLCzeta (show PLCz1 ELISA Kits), PLCeta), only PLCbeta has been linked to 2-AG synthesis. Here we demonstrate that 8-CPT (show DHDDS ELISA Kits)-2Me-cAMP, a selective agonist of the cAMP sensor protein Epac, enhances 2-AG-mediated synaptic depress...

  2. Data suggest that Epac1 reduces formation of the NLRP3 (show NLRP3 ELISA Kits) inflammasome to reduce inflammatory responses in the retinal vasculature.

  3. Results demonstrate that Epac1 plays an important role in regulating energy balance and glucose homeostasis by promoting leptin (show LEP ELISA Kits) expression and secretion in white adipose tissue.

  4. data demonstrate that endogenous PGE2, EP2 (show SPAG11A ELISA Kits) receptors, and EPAC are prerequisites for maximal LPS (show TLR4 ELISA Kits)-induced IL-33 (show IL33 ELISA Kits) expression and that exogenous PGE2 can amplify IL-33 (show IL33 ELISA Kits) production via EP2 (show SPAG11A ELISA Kits) and EP4 (show PTGER4 ELISA Kits) receptors.

  5. Epac1 is involved in AC5 (show ADCY5 ELISA Kits)-mediated catecholamine stress-induced cardiac fibrosis. Epac1 is involved in AC5 (show ADCY5 ELISA Kits)-mediated elongation of atrial fibrillation.

  6. Within heart mitochondria, different Epac1 microdomains control myocardial cell death.

  7. GRK2 inhibits Epac1-to-Rap1 signaling by phosphorylation of Epac1 at Ser-108 in the Disheveled/Egl-10/pleckstrin domain, inhibiting agonist-induced Epac1 translocation to the plasma membrane, reducing Rap1 activation.

  8. DPP4i restores cardiac remodeling and apoptosis caused by the pathological decline in circulating GLP-1 in response to pressure overload. EPAC1 is essential for cardiomyocyte survival via the cAMP/Rap1 activation independently of PKA.

  9. Epac2 (show RAPGEF4 ELISA Kits), but not Epac1 has a role in decreasing severity of ischemic retinopathy after retinal ischemia/reperfusion injury

  10. Epac1 deficiency attenuates neointima formation through, at least in part, inhibition of SMC (show DYM ELISA Kits) migration, in which a decrease in Ca(2 (show CA2 ELISA Kits)+) influx and a suppression of cofilin (show CFL1 ELISA Kits)-mediated lamellipodia formation occur.

Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) Antigen Profile

Antigen Summary

binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner

Alternative names and synonyms associated with Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3)

  • Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3) Elisa Kit
  • Rap guanine nucleotide exchange factor (GEF) 3 (rapgef3) Elisa Kit
  • Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3) Elisa Kit
  • 2310016P22Rik Elisa Kit
  • 9330170P05Rik Elisa Kit
  • bcm910 Elisa Kit
  • CAMP-GEFI Elisa Kit
  • Epac Elisa Kit
  • Epac1 Elisa Kit
  • HSU79275 Elisa Kit
  • RAPGEF3 Elisa Kit
  • si:dkey-27m20.2 Elisa Kit

Protein level used designations for RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3 , RAP guanine-nucleotide-exchange factor 3 , exchange protein directly activated by cAMP 1 , rap guanine nucleotide exchange factor 3 , Rap1 guanine-nucleotide exchange factor , rap guanine nucleotide exchange factor 3-like , 9330170P05Rik , EPAC 1 , Rap1 guanine-nucleotide-exchange factor directly activated by cAMP , cAMP-regulated guanine nucleotide exchange factor I , exchange factor directly activated by cAMP 1 , cAMP-GEFI , cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI) , epac 1

GENE ID SPECIES
426888 Gallus gallus
467198 Pan troglodytes
486591 Canis lupus familiaris
535383 Bos taurus
703967 Macaca mulatta
733186 Xenopus laevis
100174087 Pongo abelii
100320646 Danio rerio
100399583 Callithrix jacchus
100473947 Ailuropoda melanoleuca
100560594 Anolis carolinensis
10411 Homo sapiens
223864 Mus musculus
59326 Rattus norvegicus
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