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Browse our Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) ELISA Kits

Full name:
Rap Guanine Nucleotide Exchange Factor (GEF) 3 ELISA Kits (RAPGEF3)
On www.antibodies-online.com are 0 Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) ELISA Kits from different suppliers available. Additionally we are shipping Rap Guanine Nucleotide Exchange Factor (GEF) 3 Antibodies (65) and Rap Guanine Nucleotide Exchange Factor (GEF) 3 Proteins (8) and many more products for this protein. A total of 85 Rap Guanine Nucleotide Exchange Factor (GEF) 3 products are currently listed.
Synonyms:
2310016P22Rik, 9330170P05Rik, bcm910, CAMP-GEFI, Epac, Epac1, HSU79275, RAPGEF3, si:dkey-27m20.2
list all ELISA KIts Gene Name GeneID UniProt
Human RAPGEF3 RAPGEF3 10411 O95398
Mouse RAPGEF3 RAPGEF3 223864 Q8VCC8
Rat RAPGEF3 RAPGEF3 59326 Q9Z1C8

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More ELISA Kits for Rap Guanine Nucleotide Exchange Factor (GEF) 3 Interaction Partners

Cow (Bovine) Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. prostacyclin regulates bone growth via the Epac/Rap1 pathway

Xenopus laevis Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. cAMP binds Xepac protein enabling it to activate the Ca2 (show CA2 ELISA Kits)+ pathway, which is necessary to start and maintain X. laevis vitellogenin (show VTG ELISA Kits) uptake.

Human Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. The overexpression of EPAC1 can be used as a marker to predict the outcome of patients with GC, and EPAC1 represents a potential therapeutic modality for treating gastric cancer

  2. our data provide new insight into the essential role of Epac1 in regulating growth of ovarian cancer cells and suggest that Epac1 might represent an attractive therapeutic target for treatment of ovarian cancer.

  3. These findings suggested Epac is connected to the SDF-1 (show CXCL12 ELISA Kits) signaling cascades. In conclusion, our study revealed that Epac plays a role in human mesenchymal stem cells (hMSCs)homing by promoting adhesion and migration. Appropriate manipulation of Epac may enhance the homing of hMSCs and facilitate their future clinical applications.

  4. EPAC activity is increased in arterial endothelial cells exposed to laminar-fluid shear stress, activation of EPAC1, and its activation of Rap1, plays a role in promoting alignment and elongation of these cells in the direction of flow.

  5. EPAC activation consistently reverses clinical and experimental impairment of neutrophil phagocytosis. EPAC signals through Rap-1 (show RABGEF1 ELISA Kits) and bypasses RhoA (show RHOA ELISA Kits). EPAC activation represents a novel potential means by which to reverse impaired neutrophil phagocytosis.

  6. The cAMP exerted divergent effects on proliferation and promoted cell adhesion of different neuroendocrine cell types, these effects being mediated by both Epac and PKA and involving the same effector GTPase Rap1.

  7. Impaired microtubule dynamics, due to reduced EPAC1 signaling, links CFTR (show CFTR ELISA Kits) function to cystic fibrosis (show S100A8 ELISA Kits) cellular events.

  8. Identified a conserved nuclear pore localisation signal (NPLS; amino acids 764-838 of EPAC1) in the catalytic domains of the cAMP-sensors, EPAC1 and EPAC2A. EPAC1 and EPAC2 (show RAPGEF4 ELISA Kits), display distinct subcellular distributions.

  9. Thyroid carcinoma cell lines showed no or very weak EPAC1 expression and exhibited no growth-promoting effect after EPAC stimulation.

  10. findings, coupled with the development of EPAC specific small molecule modulators, validate EPAC1 as a promising target for therapeutic interventions

Mouse (Murine) Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) interaction partners

  1. GRK2 inhibits Epac1-to-Rap1 signaling by phosphorylation of Epac1 at Ser-108 in the Disheveled/Egl-10/pleckstrin domain, inhibiting agonist-induced Epac1 translocation to the plasma membrane, reducing Rap1 activation.

  2. DPP4i restores cardiac remodeling and apoptosis caused by the pathological decline in circulating GLP-1 in response to pressure overload. EPAC1 is essential for cardiomyocyte survival via the cAMP/Rap1 activation independently of PKA.

  3. Epac2 (show RAPGEF4 ELISA Kits), but not Epac1 has a role in decreasing severity of ischemic retinopathy after retinal ischemia/reperfusion injury

  4. Epac1 deficiency attenuates neointima formation through, at least in part, inhibition of SMC (show DYM ELISA Kits) migration, in which a decrease in Ca(2 (show CA2 ELISA Kits)+) influx and a suppression of cofilin (show CFL1 ELISA Kits)-mediated lamellipodia formation occur.

  5. PDE4 (show PDE4A ELISA Kits) inhibition reduces neointima formation and inhibits VCAM-1 (show VCAM1 ELISA Kits) expression and histone methylation in an Epac-dependent manner.

  6. Epac1 deletion protected against beta-AR-induced cardiac remodelling and prevented the induction of autophagy.

  7. Epac1 induces beta2-AR-mediated masseter muscle hypertrophy without influencing slow-to-fast MHC isoform transition, probably via activation of Akt (show AKT1 ELISA Kits) and its downstream molecules and increase of CaMKII (show CAMK2G ELISA Kits)-mediated HDAC4 (show HDAC5 ELISA Kits) phosphorylation.

  8. these data show that Treg degrade ATP to adenosine via CD39, attracting DC by activating Epac1-Rap1-dependent pathways.

  9. EPAC1 was found to facilitate metastasis of pancreatic ductal carcinoma.

  10. prostacyclin regulates bone growth via the Epac/Rap1 pathway

Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) Antigen Profile

Antigen Summary

binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner

Alternative names and synonyms associated with Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3)

  • Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3) Elisa Kit
  • Rap guanine nucleotide exchange factor (GEF) 3 (rapgef3) Elisa Kit
  • Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3) Elisa Kit
  • 2310016P22Rik Elisa Kit
  • 9330170P05Rik Elisa Kit
  • bcm910 Elisa Kit
  • CAMP-GEFI Elisa Kit
  • Epac Elisa Kit
  • Epac1 Elisa Kit
  • HSU79275 Elisa Kit
  • RAPGEF3 Elisa Kit
  • si:dkey-27m20.2 Elisa Kit

Protein level used designations for RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3 , RAP guanine-nucleotide-exchange factor 3 , exchange protein directly activated by cAMP 1 , rap guanine nucleotide exchange factor 3 , Rap1 guanine-nucleotide exchange factor , rap guanine nucleotide exchange factor 3-like , 9330170P05Rik , EPAC 1 , Rap1 guanine-nucleotide-exchange factor directly activated by cAMP , cAMP-regulated guanine nucleotide exchange factor I , exchange factor directly activated by cAMP 1 , cAMP-GEFI , cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI) , epac 1

GENE ID SPECIES
426888 Gallus gallus
467198 Pan troglodytes
486591 Canis lupus familiaris
535383 Bos taurus
703967 Macaca mulatta
733186 Xenopus laevis
100174087 Pongo abelii
100320646 Danio rerio
100399583 Callithrix jacchus
100473947 Ailuropoda melanoleuca
100560594 Anolis carolinensis
10411 Homo sapiens
223864 Mus musculus
59326 Rattus norvegicus
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