Browse our anti-RXFP2 (RXFP2) Antibodies

Full name:
anti-Relaxin/insulin-Like Family Peptide Receptor 2 Antibodies (RXFP2)
On www.antibodies-online.com are 62 Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) Antibodies from 13 different suppliers available. Additionally we are shipping RXFP2 Proteins (5) and RXFP2 Kits (3) and many more products for this protein. A total of 73 RXFP2 products are currently listed.
Synonyms:
Gpcr, Gpr106, Great, INSL3R, Lgr8, LGR8.1, RXFPR2
list all antibodies Gene Name GeneID UniProt
RXFP2 122042 Q8WXD0
RXFP2 140498 Q91ZZ5
RXFP2 363866  

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Most Popular Reactivities for anti-RXFP2 (RXFP2) Antibodies

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anti-Human RXFP2 Antibodies:

anti-Mouse (Murine) RXFP2 Antibodies:

anti-Rat (Rattus) RXFP2 Antibodies:

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Top referenced anti-RXFP2 Antibodies

  1. Human Polyclonal RXFP2 Primary Antibody for ELISA, WB - ABIN1535993 : Hsu, Nakabayashi, Nishi, Kumagai, Kudo, Sherwood, Hsueh: Activation of orphan receptors by the hormone relaxin. in Science (New York, N.Y.) 2002 (PubMed)

  2. Human Polyclonal RXFP2 Primary Antibody for IF, IHC (p) - ABIN615664 : Anand-Ivell, Relan, Balvers, Coiffec-Dorval, Fritsch, Bathgate, Ivell: Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis. in Biology of reproduction 2006 (PubMed)

More Antibodies against RXFP2 Interaction Partners

Human Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) interaction partners

  1. In the TMD (show TTN Antibodies) discovery cohort, sex-stratified analysis identified 2 additional genome-wide significant loci in females. One lying upstream of the relaxin/insulin-like family peptide receptor 2 ( RXP2) (chromosome 13, rs60249166,[OR] = 0.65, P = 3.6 x 10(-8)) was replicated among females in the meta-analysis (1-tailed P = 0.052). The other (chromosome 17, rs1531554, OR = 0.68, P = 2.9 x 10(-8)) was replicated among f

  2. Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation.

  3. Findings suggest a novel and gender-specific role for INSL3 (show INSL3 Antibodies) and cognate receptor RXFP2 signaling in ocular surface homeostasis.

  4. These results provide new mechanistic insights into the binding and activation events of RXFP1 (show RXFP1 Antibodies) and RXFP2 by their native hormone ligands.

  5. Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

  6. relaxin-2 (show RLN1 Antibodies) and its receptors RXFP1 (show RXFP1 Antibodies) and RXFP2 are expressed in GSV and their expression is significantly decreased in varicose GSV

  7. haplotype analysis of the RXFP2 gene in T222P carriers and their parents showed that this variant is linked to the previously inferred C-C-G-A-13 haplotype and consequently provides further support to the 'founder effect' hypothesis

  8. higher expression of LGR8 may facilitate tumor invasiveness in the early clinical stage of hepatocellular carcinoma.

  9. Data show that synthetic parallel dimer of the B-chain of INSL3 (show INSL3 Antibodies) is a potent inhibitor of the native peptide's binding to its receptor, RXFP2.

  10. the only clinical consequence of alterations of the INSL3 (show INSL3 Antibodies)-LGR8 system seems to be failure of the testis to normally descend in the scrotum during embryonic development, without affecting the spermatogenic and endocrine components of the testis itself

Mouse (Murine) Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) interaction partners

  1. Results suggest that DES (show DES Antibodies) causes testicular maldescent by altering the LGR8 pathway in mouse gubernaculum testis cells.

  2. The results displayed that INSL3 (show INSL3 Antibodies) changed RXFP2 expression in mouse gubernaculum testis cells in vitro

  3. data suggest a novel role for Rln (show RLN1 Antibodies) in craniofacial skeletal development and metabolism through Rxfp2

  4. Rxfp1 (show RXFP1 Antibodies), Rxfp2, and Nr3c1 (show NR3C1 Antibodies) mRNAs were expressed on the developing maxilla and mandible, Meckel's cartilage, tongue, and tooth primordia between mouse embryonic days 13.5-18.5.

  5. Spermatogonial stem cells undergo drastic depletion in the cryptorchid testes of RXFP2 deficient mice.

  6. Data suggest that Insl3 (show INSL3 Antibodies)/Rxfp2 (insulin-like peptide 3 (show INSL3 Antibodies)/relaxin receptor 2) signaling is important for testicular descent; however, germ-cell deletion of Rxfp2 did not affect spermatogenesis, germ cell survival, or male fertility.

  7. Prenatal exposure to diethylstilbestrol increased the expression of LGR8 mRNA in the mouse gubernaculum testis.

  8. A deficiency for Rxfp2 on Cav1 (show CAV1 Antibodies)-deficient background led to more than a 2-fold increase in the incidence of uterine cysts.

  9. A mouse model was created containing a novel missense mutation in Relaxin/insulin-like family peptide receptor 2 which likely prevents binding to its ligand, Insulin-like peptide 3 (show INSL3 Antibodies), resulting in failure of the transabdominal phase of testicular descent.

  10. RXFP2 signaling pathway plays an important role in mediating androgen action to stimulate gubernaculum development during inguinoscrotal testis descent.

RXFP2 Antigen Profile

Antigen Summary

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with RXFP2

  • relaxin/insulin-like family peptide receptor 2 (RXFP2) antibody
  • relaxin/insulin-like family peptide receptor 2 (Rxfp2) antibody
  • Gpcr antibody
  • Gpr106 antibody
  • Great antibody
  • INSL3R antibody
  • Lgr8 antibody
  • LGR8.1 antibody
  • RXFPR2 antibody

Protein level used designations for RXFP2

G protein coupled receptor affecting testicular descent , G-protein coupled receptor 106 , G-protein coupled receptor affecting testicular descent , leucine-rich repeat-containing G protein-coupled receptor 8 , leucine-rich repeat-containing G-protein coupled receptor 8 , relaxin family peptide receptor 2 , relaxin receptor 2 , G protein-coupled receptor 106 , INSL3 receptor

GENE ID SPECIES
122042 Homo sapiens
140498 Mus musculus
363866 Rattus norvegicus
450220 Canis lupus familiaris
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