Browse our anti-Metalloproteinase Inhibitor 2 (TIMP2) Antibodies

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anti-Metalloproteinase Inhibitor 2 Antibodies (TIMP2)
On www.antibodies-online.com are 326 Metalloproteinase Inhibitor 2 (TIMP2) Antibodies from 31 different suppliers available. Additionally we are shipping Metalloproteinase Inhibitor 2 Kits (105) and Metalloproteinase Inhibitor 2 Proteins (45) and many more products for this protein. A total of 488 Metalloproteinase Inhibitor 2 products are currently listed.
Synonyms:
CSC-21K, D11Bwg1104e, DDC8, etID32613.12, fa96h09, Timp-2, timp2, wu:fa96h09, zgc:136726
list all antibodies Gene Name GeneID UniProt
TIMP2 7077 P16035
TIMP2 29543 P30121
TIMP2 21858  

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All available anti-Metalloproteinase Inhibitor 2 Antibodies

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Top referenced anti-Metalloproteinase Inhibitor 2 Antibodies

  1. Human Polyclonal TIMP2 Primary Antibody for IHC (p), ELISA - ABIN3044332 : Xu, Ling, Zhu, Fan, Zhang: The effect of 2,3,4',5-tetrahydroxystilbene-2-0-?-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms. in European journal of pharmacology 2013 (PubMed)
    Show all 7 references for 3044332

  2. Human Polyclonal TIMP2 Primary Antibody for WB - ABIN3043540 : Jin, Jiang, Yang, Zhang, Yang, Zhang, Li, Yang, Ma: Acipimox attenuates atherosclerosis and enhances plaque stability in ApoE-deficient mice fed a palmitate-rich diet. in Biochemical and biophysical research communications 2012 (PubMed)
    Show all 7 references for 3043540

  3. Human Polyclonal TIMP2 Primary Antibody for IF (p), IHC (p) - ABIN668346 : Fang, Wu, Huang: Raloxifene upregulated mesangial cell MMP-2 activity via ER-? through transcriptional regulation. in Cell biochemistry and biophysics 2013 (PubMed)
    Show all 6 references for 668346

  4. Human Monoclonal TIMP2 Primary Antibody for IF - ABIN396587 : Alakus, Afriani, Warnecke-Eberz, Bollschweiler, Fetzner, Drebber, Metzger, Hölscher, Mönig: Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer. in World journal of surgery 2010 (PubMed)
    Show all 5 references for 396587

  5. Human Polyclonal TIMP2 Primary Antibody for IF, ELISA - ABIN1533420 : Hu, Cai, Hu, Patel, Bard, Jamison, Coling: Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 (PubMed)
    Show all 2 references for 1533420

More Antibodies against Metalloproteinase Inhibitor 2 Interaction Partners

Human Metalloproteinase Inhibitor 2 (TIMP2) interaction partners

  1. High TIMP2 expression is associated with acute kidney injury.

  2. High TIMP2 expression is associated with acute kidney injury.

  3. expression of TIMP2 was inversely associated with miR (show MLXIP Antibodies)-106a in nodule tissues. Apoptotic body was also seen under electron microscope accompanied by silencing of miR (show MLXIP Antibodies)-106a. Together, this data indicated that miR (show MLXIP Antibodies)-106a may act as an oncogene (show RAB1A Antibodies) and contribute to gastric cancer development.

  4. Data show that the mean values for TIMP1 (show TIMP1 Antibodies), TIMP2 and MMP2 (show MMP2 Antibodies) were lower in survivors, MMP9 (show MMP9 Antibodies) was higher in survivors.

  5. Urine [TIMP-2]*[IGFBP7 (show IGFBP7 Antibodies)] is a promising candidate for early detection of AKI, especially in ruling-out AKI

  6. We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7 (show MMP7 Antibodies), MMP-10 (show MMP10 Antibodies) and TIMP-1 (show TIMP1 Antibodies) correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the disease. MMP-10 (show MMP10 Antibodies), MMP-7 (show MMP7 Antibodies), TIMP-1 (show TIMP1 Antibodies), TIMP-2 were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.

  7. At hospital admission, all viral gastroenteritis (GE) patients viral gastroenteritis (GE) patients demonstrated increased MMP-9 (show MMP9 Antibodies) and decreased MMP-2 (show MMP2 Antibodies) and TIMP-2 serum levels; kinetics of serum MMP-2 (show MMP2 Antibodies), MMP-9 (show MMP9 Antibodies), and TIMP-2 levels were similar among the viral GE patients but distinct from bacterial enteritis patients; involvement of MMPs and TIMPs in the pathophysiology of gastrointestinal symptoms likely varies depending on the

  8. Meta-analysis indicated that urinary [TIMP-2].[IGFBP7 (show IGFBP7 Antibodies)] may be a reliable biomarker for the early detection of acute kidney injury in adults.

  9. Results show that resistant hypertension was associated with higher TIMP-2 levels and low MMP-2 (show MMP2 Antibodies)/TIMP-2 ratio, suggesting that these regulators of ECM (show MMRN1 Antibodies) remodeling play a key role in blood pressure control in this high-risk subset of hypertensive individuals.

  10. TIMP-2 is both expressed and secreted preferentially by cells of distal tubule origin, while IGFBP7 (show IGFBP7 Antibodies) is equally expressed across tubule cell types yet preferentially secreted by cells of proximal tubule origin. In human kidney tissue, strong staining of IGFBP7 (show IGFBP7 Antibodies) was seen in the luminal brush-border region of a subset of proximal tubule cells, and TIMP-2 stained intracellularly in distal tubules.

Cow (Bovine) Metalloproteinase Inhibitor 2 (TIMP2) interaction partners

  1. Data indicate the involvement of PKC-alpha (show PKCa Antibodies) in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB (show NFKB1 Antibodies)-MT1-MMP (show MMP14 Antibodies)-dependent and -independent pathway.

  2. A differential pattern of matrix metalloproteinase-2 (show MMP2 Antibodies) and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.

  3. MMP-14 (show MMP14 Antibodies), MMP-2 (show MMP2 Antibodies) and TIMP-2 are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.

  4. Results describe distinct changes in expression of MMP2 (show MMP2 Antibodies), MMP14 (show MMP14 Antibodies), and the metallopeptidase (show ECEL1 Antibodies) inhibitor TIMP2 between different phases of the estrous cycle indicating an endocrine regulation.

  5. Production of TIMP-1 (show TIMP1 Antibodies) was augmented by IL-1alpha, TNFalpha (show TNF Antibodies), and hepatocyte growth factor (show HGF Antibodies) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 mRNA was not affected by any treatments.

  6. the different temporal expression patterns of TIMP-1 (show TIMP1 Antibodies) and TIMP-2 suggest that TIMP-1 (show TIMP1 Antibodies) may be important for luteal formation and development, while TIMP-2 may play significant roles during luteal development and maintenance

  7. Identification, purification and partial characterization of timp-2 in bovine pulmonary artery smooth muscle

  8. Results describe the isolation of matrix metalloproteinase 2 (MMP-2 (show MMP2 Antibodies)) from the MMP-2 (show MMP2 Antibodies)/tissue inhibitor of metalloproteinase 2 (TIMP-2) complex, and the characterization of both isolated MMP-2 (show MMP2 Antibodies) and the complex itself.

  9. oxidants inactivate TIMP-2, and the resulting activation of MMP-2 (show MMP2 Antibodies) subsequently inhibits Na+ dependent Ca2 (show CA2 Antibodies)+ uptake in the microsomes

  10. TIMP-2 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.

Horse (Equine) Metalloproteinase Inhibitor 2 (TIMP2) interaction partners

  1. The pathology of laminitis is associated with increased and lowered transcription of MMP-14 (show MMP14 Antibodies) and TIMP-2, respectively.

Mouse (Murine) Metalloproteinase Inhibitor 2 (TIMP2) interaction partners

  1. the protein expression levels of TIMP-2 and PBEF (show NAMPT Antibodies) in cloned placentae, were examined.

  2. demonstrate that TIMP-2 plays a greater protective role than TIMP-1 (show TIMP1 Antibodies) during the pathogenesis of atherosclerosis

  3. Further investigation of MMP2 (show MMP2 Antibodies) inhibitors of TIMP2/TIMP4 (show TIMP4 Antibodies) showed an upregulated TIMP2 expression, but not TIMP4 (show TIMP4 Antibodies). low-dose pre-radiation attenuates the skin inflammation and ROS (show ROS1 Antibodies) production induced by medium-dose UV radiation

  4. TIMP2 and TIMP3 (show TIMP3 Antibodies) play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function

  5. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (show MAPK14 Antibodies) signaling pathway.

  6. High TIMP2 expression is associated with liver fibrosis.

  7. TIMP2 promotes kidney injury through metalloproteinase (MMP)2 (show MMP2 Antibodies) activation

  8. Gene expression of Mmp-12 (show MMP12 Antibodies) and Mmp-13 (show MMP13 Antibodies), and Timp-1 (show TIMP1 Antibodies) was strongly upregulated at all time points in RD compared with controls. Timp-2, Mmp-2 (show MMP2 Antibodies), and Mmp-9 (show MMP9 Antibodies) expression was modest.

  9. Data indicate a significantly increased expression of type I collagen, TIMP-2, TGF-beta (show TGFB1 Antibodies), PAI-1 (show SERPINE1 Antibodies) and RAGE (show AGER Antibodies) in diabetic db/db (show LEPR Antibodies) cells.

  10. This study suggests that miR-17 participates in the regulation of cardiac matrix remodeling and provides a novel therapeutic approach using miR-17 inhibitors to prevent remodeling and heart failure after MI.

Zebrafish Metalloproteinase Inhibitor 2 (TIMP2) interaction partners

  1. To further study the function of TIMP-2 in development, we utilized zebrafish as an experimental model system

  2. membrane-type 1 metalloproteinase, gelatinase A (show MMP2 Antibodies) , and tissue inhibitor 2 of metalloproteinases mRNA transcripts were expressed in the blastema

Metalloproteinase Inhibitor 2 (TIMP2) Antigen Profile

Antigen Summary

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Alternative names and synonyms associated with Metalloproteinase Inhibitor 2 (TIMP2)

  • TIMP metallopeptidase inhibitor 2 (TIMP2) antibody
  • TIMP metallopeptidase inhibitor 2 (Timp2) antibody
  • tissue inhibitor of metalloproteinase 2 (Timp2) antibody
  • tissue inhibitor of metalloproteinase 2a (timp2a) antibody
  • CSC-21K antibody
  • D11Bwg1104e antibody
  • DDC8 antibody
  • etID32613.12 antibody
  • fa96h09 antibody
  • Timp-2 antibody
  • timp2 antibody
  • wu:fa96h09 antibody
  • zgc:136726 antibody

Protein level used designations for TIMP2

TIMP-2 , metalloproteinase inhibitor 2 , tissue inhibitor of metalloproteinase 2 , tissue inhibitor of metalloproteinases 2 , collagenase inhibitor , tissue inhibitor of mettaloproteinase 2 , tissue inhibitor of metalloproteinase-2 , tissue inhibitor of matrix metalloproteinase-2 , metalloproteinase inhibitor TIMP-2

GENE ID SPECIES
7077 Homo sapiens
29543 Rattus norvegicus
282093 Bos taurus
100008689 Oryctolagus cuniculus
374178 Gallus gallus
396988 Sus scrofa
100034134 Equus caballus
403633 Canis lupus familiaris
743167 Pan troglodytes
100217406 Ovis aries
21858 Mus musculus
100135629 Cavia porcellus
359835 Danio rerio
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