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GPR21 has a critical function in coordinating macrophage proinflammatory activity in the context of obesity-induced insulin (show INS ELISA Kits) resistance
these findings suggest that GPR21 may play an important role in regulating body weight and glucose metabolism.
This gene encodes a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium.
probable G-protein coupled receptor 21
, G protein-coupled receptor GPR21