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anti-Mouse (Murine) LGALS1 Antibodies:
anti-Human LGALS1 Antibodies:
anti-Rat (Rattus) LGALS1 Antibodies:
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Mouse (Murine) Polyclonal LGALS1 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899423
Silva-Monteiro, Reis Lorenzato, Kenji Nihei, Junqueira, Rabinovich, Hsu, Liu, Savino, Chammas, Villa-Verde: Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. in The American journal of pathology 2007
Show all 9 Pubmed References
Human Polyclonal LGALS1 Primary Antibody for CyTOF, FACS - ABIN4899422
Yazawa, Geddes-Sweeney, Cedeno-Laurent, Walley, Barthel, Opperman, Liang, Lin, Schatton, Laga, Mihm, Qureshi, Widlund, Murphy, Dimitroff: Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential. in The Journal of investigative dermatology 2015
Show all 5 Pubmed References
Human Polyclonal LGALS1 Primary Antibody for IHC, IHC (p) - ABIN4313208
Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006
Show all 2 Pubmed References
Human Monoclonal LGALS1 Primary Antibody for IF, IP - ABIN561662
Tan, Tan, Lin, Lim, Hew, Chung: Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells. in Molecular & cellular proteomics : MCP 2008
Show all 2 Pubmed References
Human Polyclonal LGALS1 Primary Antibody for IF (p), IHC (p) - ABIN718586
Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. in Biology of sex differences 2015
Human Monoclonal LGALS1 Primary Antibody for ELISA, FACS - ABIN5582500
Couraud, Casentini-Borocz, Bringman, Griffith, McGrogan, Nedwin: Molecular cloning, characterization, and expression of a human 14-kDa lectin. in The Journal of biological chemistry 1989
Human Polyclonal LGALS1 Primary Antibody for IF, WB - ABIN517485
Doe, Wuebbles, Allred, Rooney, Elorza, Burkin: Transgenic overexpression of the ?7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A. in Journal of cell science 2011
Human Polyclonal LGALS1 Primary Antibody for IF, IHC (p) - ABIN2473743
Resnick: Should the "worst case scenario" be universal for chloramines? in Nephrology news & issues 1990
Show all 2 Pubmed References
Human Polyclonal LGALS1 Primary Antibody for ELISA, WB - ABIN2473744
Camby, Le Mercier, Lefranc, Kiss: Galectin-1: a small protein with major functions. in Glycobiology 2006
Show all 2 Pubmed References
Gal1 protein is essential for efficient liver regeneration following partial hepatectomy through the regulation of liver inflammation, hepatic cell proliferation, and the control of lipid storage in the regenerating liver.
findings show that galectin-1 (Gal-1), an immunoregulatory lectin widely expressed in mucosal tissues, contributes to Y. enterocolitica pathogenicity by undermining protective antibacterial responses.
Gal-1 functions as an important regulator in RNV and offers a promising strategy for the treatment of RNV diseases, such as proliferative diabetic retinopathy and retinopathy of prematurity.
These findings demonstrate that galectin-1 is required for i.v. tolerance induction, likely via induction of tolerogenic DCs leading to enhanced development of Tr1 (show TXNRD1 Antibodies) cells, Treg cells, and downregulation of proinflammatory responses.
this study shows that galectin-1 secreted by Sertoli cells plays a pivotal role in the differentiation of functionally tolerogenic dendritic cells
analysis of the effect of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator
Tumor-driven, unremitting expression of Satb1 (show SATB1 Antibodies) in activated Zbtb46 (show ZNF340 Antibodies)+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 and IL-6 (show IL6 Antibodies).
Gal-1 does not play a role in the systemic immunosuppressive effect of Mesenchymal stem cells.
Galectin-1 has a role in driving lymphoma CD20 (show MS4A1 Antibodies) immunotherapy resistance in a mouse model
These findings highlight the importance of the inflammatory micro-environment of mucosal tissues in modulating intestinal epithelial cells susceptibility to the immunoregulatory lectin Gal-1 and its role in epithelial cell homeostasis.
we found that galectin-1 was a novel modulator of MDR1 (show TBC1D9 Antibodies) by proteomic analysis of a model system of leukemia cell lines
Data found Gal-1 to induce EMT (show ITK Antibodies) and gastric cancer (GC) cell migration and invasion. Also, Gal-1 up-regulated Gli1 (show GLI1 Antibodies) expression and beta1 integrin was responsible for Gal-1-induced Gli1 (show GLI1 Antibodies) expression and EMT (show ITK Antibodies).
Galectin-1-driven production of SDF-1 (show CXCL12 Antibodies) in pancreatic stellate cells through activation of NF-kappaB (show NFKB1 Antibodies) promotes metastasis in pancreatic ductal adenocarcinoma.
Gal-1 expression by MM cells was upregulated in hypoxic conditions and stable knockdown of hypoxia inducible factor-1alpha significantly downregulated its expression
Gal1 may be a useful marker for determining whether morphologic changes in oral cells are reactive or neoplastic
The aim of this study was to analyze the syncytium formation abilities of BeWo cells that were gal-1 silenced.
Studies provide evidence that galectin-1 belongs to the group of potential pathogenic molecules in systemic lupus erythematosus. [review]
an intact dimer interface of Gal-1 is required for it to positively regulate H-rasG12V nanoclustering, but negatively K-rasG12V nanoclustering.
Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.
Galectin-1 and Galectin-3 (show LGALS3 Antibodies) are novel-binding partners for human FVIII (show F8 Antibodies). Gal-1 binding can influence the procoagulant activity of FVIII (show F8 Antibodies).
Data suggest that galectin-1 and VEGFR-2 (show KDR Antibodies) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (show KDR Antibodies) in luteal cells.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1, LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 (show LGALS9 Antibodies) mRNA would display a differential expression pattern in the endometrium.
The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.
Gal-1 may serve as an adhesion molecule (show NCAM1 Antibodies) to interact with both cells and laminins
Gal-1 is expressed in a wide range of porcine tissues, including striated (show NSDHL Antibodies) muscle, liver, lung, brain, kidney, spleen, and intestine
LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
lectin, galactoside-binding, soluble, 1
, galectin 1
, lectin, galactoside-binding, soluble, 1 (galectin 1)
, 14 kDa lectin
, 14K beta-galactoside-binding lectin
, beta-galactoside-binding lectin
, galectin CG-1B
, Beta-galactoside-binding lectin L-14-I
, Lactose-binding lectin 1
, Lectin galactoside-binding soluble 1
, S-Lac lectin 1
, beta-galactoside binding protein
, beta-galactoside-binding lectin L-14-I
, lactose-binding lectin 1
, lectin galactoside-binding soluble 1
, 14 kDa laminin-binding protein
, beta-galactoside-binding protein 14kDa
, putative MAPK-activating protein PM12
, RL 14.5
, lectin, galactose binding, soluble 1