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Human LGALS1 ELISA Kit for Sandwich ELISA - ABIN843103
Wu, Goan, Chang, Yang, Chang, Cheng, Wu, Zgoda, Chen, Liao: Qualification and Verification of Serological Biomarker Candidates for Lung Adenocarcinoma by Targeted Mass Spectrometry. in Journal of proteome research 2015
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Mouse (Murine) LGALS1 ELISA Kit for Sandwich ELISA - ABIN2684859
Gauthier, Rossi, Roux, Termine, Schiff: Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering. in Proceedings of the National Academy of Sciences of the United States of America 2002
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findings show that galectin-1 (Gal-1), an immunoregulatory lectin widely expressed in mucosal tissues, contributes to Y. enterocolitica pathogenicity by undermining protective antibacterial responses.
Gal-1 functions as an important regulator in RNV and offers a promising strategy for the treatment of RNV diseases, such as proliferative diabetic retinopathy and retinopathy of prematurity.
These findings demonstrate that galectin-1 is required for i.v. tolerance induction, likely via induction of tolerogenic DCs leading to enhanced development of Tr1 cells, Treg cells, and downregulation of proinflammatory responses.
this study shows that galectin-1 secreted by Sertoli cells plays a pivotal role in the differentiation of functionally tolerogenic dendritic cells
analysis of the effect of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator
Tumor-driven, unremitting expression of Satb1 (show SATB1 ELISA Kits) in activated Zbtb46+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 and IL-6 (show IL6 ELISA Kits).
Gal-1 does not play a role in the systemic immunosuppressive effect of Mesenchymal stem cells.
Galectin-1 has a role in driving lymphoma CD20 (show MS4A1 ELISA Kits) immunotherapy resistance in a mouse model
These findings highlight the importance of the inflammatory micro-environment of mucosal tissues in modulating intestinal epithelial cells susceptibility to the immunoregulatory lectin Gal-1 and its role in epithelial cell homeostasis.
results unveil a dual role of endogenous versus exogenous Gal-1 in the control of autoimmune testis inflammation.
Galectin-1-driven production of SDF-1 (show CXCL12 ELISA Kits) in pancreatic stellate cells through activation of NF-kappaB (show NFKB1 ELISA Kits) promotes metastasis in pancreatic ductal adenocarcinoma.
Gal-1 expression by MM cells was upregulated in hypoxic conditions and stable knockdown of hypoxia inducible factor-1alpha significantly downregulated its expression
Gal1 may be a useful marker for determining whether morphologic changes in oral cells are reactive or neoplastic
The aim of this study was to analyze the syncytium formation abilities of BeWo cells that were gal-1 silenced.
Studies provide evidence that galectin-1 belongs to the group of potential pathogenic molecules in systemic lupus erythematosus. [review]
an intact dimer interface of Gal-1 is required for it to positively regulate H-rasG12V nanoclustering, but negatively K-rasG12V nanoclustering.
Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.
Galectin-1 and Galectin-3 (show LGALS3 ELISA Kits) are novel-binding partners for human FVIII (show F8 ELISA Kits). Gal-1 binding can influence the procoagulant activity of FVIII (show F8 ELISA Kits).
Proteomics of the interstitial fluid in subcutaneous adipose tissue in vivo identified a novel adipokine, galectin-1, with a potential role in the pathophysiology of type 2 diabetes.
Suggest that galectin-1 is a protective factor against the development of digital vasculopathy in systemic sclerosis.
Data suggest that galectin-1 and VEGFR-2 (show KDR ELISA Kits) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (show KDR ELISA Kits) in luteal cells.
The relative abundance of PIBF (show PIBF1 ELISA Kits), LGALS1, LGALS3 (show LGALS2 ELISA Kits), LGALS3BP (show LGALS3BP ELISA Kits), and LGALS9 (show LGALS9 ELISA Kits) mRNA would display a differential expression pattern in the endometrium.
The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.
Gal-1 may serve as an adhesion molecule (show NCAM1 ELISA Kits) to interact with both cells and laminins
Gal-1 is expressed in a wide range of porcine tissues, including striated (show NSDHL ELISA Kits) muscle, liver, lung, brain, kidney, spleen, and intestine
LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
lectin, galactoside-binding, soluble, 1
, galectin 1
, lectin, galactoside-binding, soluble, 1 (galectin 1)
, 14 kDa lectin
, 14K beta-galactoside-binding lectin
, beta-galactoside-binding lectin
, galectin CG-1B
, Beta-galactoside-binding lectin L-14-I
, Lactose-binding lectin 1
, Lectin galactoside-binding soluble 1
, S-Lac lectin 1
, beta-galactoside binding protein
, beta-galactoside-binding lectin L-14-I
, lactose-binding lectin 1
, lectin galactoside-binding soluble 1
, 14 kDa laminin-binding protein
, beta-galactoside-binding protein 14kDa
, putative MAPK-activating protein PM12
, RL 14.5
, lectin, galactose binding, soluble 1