Browse our MLXIPL Proteins (MLXIPL)

Full name:
MLX Interacting Protein-Like Proteins (MLXIPL)
On www.antibodies-online.com are 3 MLX Interacting Protein-Like (MLXIPL) Proteins from 2 different suppliers available. Additionally we are shipping MLXIPL Antibodies (119) and many more products for this protein. A total of 126 MLXIPL products are currently listed.
Synonyms:
bHLHd14, CHREBP, MIO, MLXIPL, MONDOB, Wbscr14, WS-bHLH
list all proteins Gene Name GeneID UniProt
MLXIPL 51085 Q9NP71
MLXIPL 58805 Q99MZ3
Rat MLXIPL MLXIPL 171078 Q8VIP2

Show all synonyms

MLXIPL Proteins (MLXIPL) by Origin

Select your origin of interest

More Proteins for MLXIPL Interaction Partners

Human MLX Interacting Protein-Like (MLXIPL) interaction partners

  1. A nutrient-sensitive mTOR (show FRAP1 Proteins)/ChREBP regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  2. these findings support a carbohydrate-mediated, ChREBP-driven mechanism that contributes to hepatic insulin (show INS Proteins) resistance.

  3. results indicated that the age and total cholesterol concentrations were independent influential factors of ChREBP methylation and DNMT1 (show DNMT1 Proteins) variants could probably influence LDL-C to further modify ChREBP DNA methylation (show HELLS Proteins)

  4. p = 6.69 x 10(-9) ] on chr7 at the carbohydrate-responsive element-binding protein-encoding (MLXIPL) gene locus displayed significant protective characteristics, while another variant rs6982502 [0.76 (0.68-0.84); p = 5.31 x 10(-7) ] on chr8 showed similar but weaker properties.

  5. ChREBP role in non-alcoholic fatty liver disease.The involvement of ChREBP in FASN (show FASN Proteins) promoter histone modification.

  6. This cross-sectional study suggests that MLXIPL rs3812316 genotypes may be associated with Triglyceride levels. there were significantly different genotype distributions in two TG categories: (1) subjects with normal TG values had a significantly higher G allele frequency than those with elevated TG levels

  7. The results revealed the novel mechanism by which HNF-4alpha (show HNF4A Proteins) promoted ChREBP transcription in response to glucose, and also demonstrated that ChREBP-alpha and HNF-4alpha (show HNF4A Proteins) synergistically increased ChREBP-beta transcription.

  8. High glucose-mediated induction of PDGF-C (show PDGFC Proteins) via ChREBP in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  9. Evaluation of the conservation of ChREBP and MondoA (show MLXIP Proteins) sequences demonstrate that MondoA (show MLXIP Proteins) is better conserved and potentially mediates more ancient function in glucose metabolism.

  10. Metformin down-regulates high-glucose-induced TXNIP (show TXNIP Proteins) transcription by inactivating ChREBP and FOXO1 (show FOXO1 Proteins) in endothelial cells, partially through AMP-activated protein kinase (show PRKAA2 Proteins) activation

Mouse (Murine) MLX Interacting Protein-Like (MLXIPL) interaction partners

  1. A nutrient-sensitive mTOR (show FRAP1 Proteins)/ChREBP regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  2. findings suggest that a previously unknown link exists between ChREBP and the regulation of cholesterol synthesis that affects liver injury.

  3. findings also identified a role for ChREBP in regulating SREBP2 (show SREBF2 Proteins)-dependent cholesterol metabolism.

  4. these findings support a carbohydrate-mediated, ChREBP-driven mechanism that contributes to hepatic insulin (show INS Proteins) resistance.

  5. a high complex carbohydrate diet selectively increases hepatic ChREBPbeta expression, which associates with hepatic steatosis but not insulin (show INS Proteins) resistance. In contrast, a high fat diet reduces adipose ChREBP, which associates with inflammation and insulin (show INS Proteins) resistance.

  6. the synergistic action of ChREBP and SREBP-1c is necessary for the maximal induction of Elovl6 expression in the liver.

  7. The results revealed the novel mechanism by which HNF-4alpha (show HNF4A Proteins) promoted ChREBP transcription in response to glucose, and also demonstrated that ChREBP-alpha and HNF-4alpha (show HNF4A Proteins) synergistically increased ChREBP-beta transcription.

  8. High glucose-mediated induction of PDGF-C (show PDGFC Proteins) via ChREBP in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  9. Adipose tissue mTORC2 (show CRTC2 Proteins) regulates via Rictor ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.

  10. Targeted deletion of ChREBP in bone marrow cells resulted in accelerated atherosclerosis progression in Ldlr (show LDLR Proteins)-/- mice with increased monocytosis, lesional macrophage accumulation, and plaque necrosis.

MLXIPL Protein Profile

Protein Summary

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Alternative names and synonyms associated with MLXIPL

  • MLX interacting protein-like (MLXIPL)
  • MLX interacting protein-like (Mlxipl)
  • bHLHd14 protein
  • CHREBP protein
  • MIO protein
  • MLXIPL protein
  • MONDOB protein
  • Wbscr14 protein
  • WS-bHLH protein

Protein level used designations for MLXIPL

MLX interacting protein-like , carbohydrate response element binding protein variant 1 , carbohydrate response element binding protein variant 2 , Williams-Beuren syndrome chromosomal region 14 protein homolog , carbohydrate responsive element binding protein , williams-Beuren syndrome chromosomal region 14 protein homolog , MLX-interacting protein-like , Mlx interactor , WS basic-helix-loop-helix leucine zipper protein , Williams Beuren syndrome chromosome region 14 , Williams-Beuren syndrome chromosome region 14 protein 1 , Williams-Beuren syndrome chromosome region 14 protein 2 , carbohydrate response element binding protein , carbohydrate-responsive element-binding protein , class D basic helix-loop-helix protein 14 , williams-Beuren syndrome chromosomal region 14 protein , MLX interacting protein-like beta , MLX interactor , Williams-Beuren syndrome chromosome region 14 homolog , putative hepatic transcription factor , WBSCR14 protein-like , Williams-Beuren syndrome chromosomal region 14 protein

GENE ID SPECIES
425603 Gallus gallus
489807 Canis lupus familiaris
100059888 Equus caballus
100170769 Sus scrofa
100438130 Pongo abelii
51085 Homo sapiens
58805 Mus musculus
788534 Bos taurus
171078 Rattus norvegicus
Selected quality suppliers for MLXIPL Proteins (MLXIPL)
Did you look for something else?